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Alicia Carmen Bort Bueno

LA QUINASA ACTIVADA POR AMP (AMPK) COMO DIANA TERAPÉUTICA EN CARCINOMA. PAPEL DE LA CAPSAICINA
30/11/2018
Dirección:
Enlaces curriculares
Publicaciones
  1. 2022 - Pharmaceutics (ver indicadores de calidad)
    Sánchez BG, Bort A, Mora-Rodríguez JM, Díaz-Laviada I. The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells. Pharmaceutics. 2022 Jan 29;14(2):329. doi: 10.3390/pharmaceutics14020329. PMID: 35214061; PMCID: PMC8880011.
  2. 2022 - Front Cell Dev Biol (ver indicadores de calidad)
    Bort A, G Sánchez B, León C, Nozal L, Mora-Rodríguez JM, Castro F, Crego AL, Díaz-Laviada I. Metabolic fingerprinting of chemotherapy-resistant prostate cancer stem cells. An untargeted metabolomic approach by liquid chromatography-mass spectrometry. Front Cell Dev Biol. 2022 Oct 17;10:1005675. doi: 10.3389/fcell.2022.1005675. PMID: 36325358; PMCID: PMC9618794.
  3. 2022 - Biomedicines (ver indicadores de calidad)
    Sebastián-Martín A, Sánchez BG, Mora-Rodríguez JM, Bort A, Díaz-Laviada I. Role of Dipeptidyl Peptidase-4 (DPP4) on COVID-19 Physiopathology. Biomedicines. 2022 Aug 19;10(8):2026. doi: 10.3390/biomedicines10082026. PMID: 36009573; PMCID: PMC9406088.
  4. 2022 - Biomedicines (ver indicadores de calidad)
    Sánchez BG, Bort A, Mora-Rodríguez JM, Díaz-Yuste A, Gasalla JM, Sánchez-Chapado M, Sebastián-Martín A, Díaz-Laviada I. A Highly Sensitive Immunoassay for Determination of Immune Response to SARS-CoV-2 in Capillary Blood Samples. Biomedicines. 2022 Nov 11;10(11):2897. doi: 10.3390/biomedicines10112897. PMID: 36428468; PMCID: PMC9687217.
  5. 2022 - Biomacromolecules (ver indicadores de calidad)
    Barrios O, Sánchez BG, Rodríguez-Prieto T, Cano J, Bort A, Gómez R, Díaz-Laviada I. Alteration of the HIF-1α/VEGF Signaling Pathway and Disruption of the Cell Cycle by Second Generation Carbosilan Dendrimers. Biomacromolecules. 2022 Dec 12;23(12):5043-5055. doi: 10.1021/acs.biomac.2c00899. Epub 2022 Nov 29. PMID: 36445323; PMCID: PMC9748942.
  6. 2021 - J Clin Med (ver indicadores de calidad)
    Sanchez BG, Gasalla JM, Sánchez-Chapado M, Bort A, Diaz-Laviada I. Increase in Ischemia-Modified Albumin and Pregnancy-Associated Plasma Protein-A in COVID-19 Patients. J Clin Med. 2021 Nov 23;10(23):5474. doi: 10.3390/jcm10235474. PMID: 34884175; PMCID: PMC8658290.
  7. 2020 - Cells (ver indicadores de calidad)
    Sánchez BG, Bort A, Vara-Ciruelos D, Díaz-Laviada I. Androgen Deprivation Induces Reprogramming of Prostate Cancer Cells to Stem-Like Cells. Cells. 2020 Jun 10;9(6):1441. doi: 10.3390/cells9061441. PMID: 32531951; PMCID: PMC7349866.
  8. 2019 - PLoS One (ver indicadores de calidad)
    Bort A, Sánchez BG, Spínola E, Mateos-Gómez PA, Rodríguez-Henche N, Díaz-Laviada I. The red pepper's spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ. PLoS One. 2019 Jan 29;14(1):e0211420. doi: 10.1371/journal.pone.0211420. PMID: 30695053; PMCID: PMC6350977.
  9. 2019 - Mol Oncol (ver indicadores de calidad)
    Bort A, Sánchez BG, Mateos-Gómez PA, Vara-Ciruelos D, Rodríguez-Henche N, Díaz-Laviada I. Targeting AMP-activated kinase impacts hepatocellular cancer stem cells induced by long-term treatment with sorafenib. Mol Oncol. 2019 May;13(5):1311-1331. doi: 10.1002/1878-0261.12488. Epub 2019 Apr 15. PMID: 30959553; PMCID: PMC6487713.
  10. 2019 - Int J Mol Sci (ver indicadores de calidad)
    Bort A, Sánchez BG, Mateos-Gómez PA, Díaz-Laviada I, Rodríguez-Henche N. Capsaicin Targets Lipogenesis in HepG2 Cells Through AMPK Activation, AKT Inhibition and PPARs Regulation. Int J Mol Sci. 2019 Apr 3;20(7):1660. doi: 10.3390/ijms20071660. PMID: 30987128; PMCID: PMC6480012.
  11. 2019 - Cancer Cell Int (ver indicadores de calidad)
    Sánchez BG, Bort A, Mateos-Gómez PA, Rodríguez-Henche N, Díaz-Laviada I. Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase. Cancer Cell Int. 2019 Mar 8;19:54. doi: 10.1186/s12935-019-0769-2. PMID: 30899201; PMCID: PMC6408806.
  12. 2018 - Sci Rep (ver indicadores de calidad)
    Bort A, Quesada S, Ramos-Torres Á, Gargantilla M, Priego EM, Raynal S, Lepifre F, Gasalla JM, Rodriguez-Henche N, Castro A, Díaz-Laviada I. Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation. Sci Rep. 2018 Mar 12;8(1):4370. doi: 10.1038/s41598-018-22690-2. PMID: 29531259; PMCID: PMC5847527.
  13. 2017 - Oncotarget (ver indicadores de calidad)
    Bort A, Spínola E, Rodríguez-Henche N, Díaz-Laviada I. Capsaicin exerts synergistic antitumor effect with sorafenib in hepatocellular carcinoma cells through AMPK activation. Oncotarget. 2017 Sep 23;8(50):87684-87698. doi: 10.18632/oncotarget.21196. PMID: 29152112; PMCID: PMC5675664.
  14. 2017 - Mol Pain (ver indicadores de calidad)
    Bort A, Alvarado-Vazquez PA, Moracho-Vilrriales C, Virga KG, Gumina G, Romero-Sandoval A, Asbill S. Effects of JWH015 in cytokine secretion in primary human keratinocytes and fibroblasts and its suitability for topical/transdermal delivery. Mol Pain. 2017 Jan;13:1744806916688220. doi: 10.1177/1744806916688220. PMID: 28326930; PMCID: PMC5302180.
  15. 2016 - Prostate Cancer Prostatic Dis (ver indicadores de calidad)
    Morell C, Bort A, Vara D, Ramos-Torres A, Rodríguez-Henche N, Díaz-Laviada I. The cannabinoid WIN 55,212-2 prevents neuroendocrine differentiation of LNCaP prostate cancer cells. Prostate Cancer Prostatic Dis. 2016 Sep;19(3):248-57. doi: 10.1038/pcan.2016.19. Epub 2016 Jun 21. PMID: 27324222; PMCID: PMC5411672.
  16. 2016 - PLoS One (ver indicadores de calidad)
    Morell C, Bort A, Vara-Ciruelos D, Ramos-Torres Á, Altamirano-Dimas M, Díaz-Laviada I, Rodríguez-Henche N. Up-Regulated Expression of LAMP2 and Autophagy Activity during Neuroendocrine Differentiation of Prostate Cancer LNCaP Cells. PLoS One. 2016 Sep 14;11(9):e0162977. doi: 10.1371/journal.pone.0162977. PMID: 27627761; PMCID: PMC5023108.
  17. 2016 - Oncotarget (ver indicadores de calidad)
    Ramos-Torres Á, Bort A, Morell C, Rodríguez-Henche N, Díaz-Laviada I. The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells. Oncotarget. 2016 Jan 12;7(2):1569-83. doi: 10.18632/oncotarget.6415. PMID: 26625315; PMCID: PMC4811481.
  18. 2012 - Dis Model Mech (ver indicadores de calidad)
    Stemmer K, Perez-Tilve D, Ananthakrishnan G, Bort A, Seeley RJ, Tschöp MH, Dietrich DR, Pfluger PT. High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney. Dis Model Mech. 2012 Sep;5(5):627-35. doi: 10.1242/dmm.009407. Epub 2012 Mar 15. PMID: 22422828; PMCID: PMC3424460.
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