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| 1 |
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Alcázar González, Alberto |
Martínez-Alonso E, Escobar-Peso A, Guerra-Pérez N, Roca M, Masjuan J, Alcázar A. Dihydropyrimidinase-Related Protein 2 Is a New Partner in the Binding between 4E-BP2 and eIF4E Related to Neuronal Death after Cerebral Ischemia. Int J Mol Sci. 2023 May 4;24(9):8246. doi: 10.3390/ijms24098246. PMID: 37175950; PMCID: PMC10179276. |
| 2 |
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Alcázar González, Alberto |
Calvo FA, Palma J, Serrano J, Cambeiro M, Meiriño R, Martin S, Azcona D, Pedrero D, Aguilar B, Delgado JM, Moran V, Viñals A, Cabello P, Panizo E, Lassaletta A, Gibert C, Sancho L, de Miguel JMF, de Sierra BA, Alcázar A, Suarez V, Alonso A, Gallardo G, Aristu J. Hospital-based proton therapy implementation during the COVID pandemic: early clinical and research experience in a European academic institution. Clin Transl Oncol. 2023 May;25(5):1268-1276. doi: 10.1007/s12094-023-03127-3. Epub 2023 Mar 24. PMID: 36961726; PMCID: PMC10036962. |
| 3 |
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Alcázar González, Alberto |
Ruiz-Blas F, Muñoz-Hisado V, Garcia-Lopez E, Moreno A, Bartolomé M, Leunda M, Martinez-Alonso E, Alcázar A, Cid C. The hidden microbial ecosystem in the perennial ice from a Pyrenean ice cave. Front Microbiol. 2023 Jan 26;14:1110091. doi: 10.3389/fmicb.2023.1110091. PMID: 36778858; PMCID: PMC9909108. |
| 4 |
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Alcázar González, Alberto |
Hoyo MLLD, Rodrigo MTF, Urcola-Pardo F, Monreal-Bartolomé A, Ruiz DCG, Borao MG, Alcázar ABA, Casbas JPM, Casas AA, Funcia MTA, Delgado JFR. The TELE-DD Randomised Controlled Trial on Treatment Adherence in Patients with Type 2 Diabetes and Comorbid Depression: Clinical Outcomes after 18-Month Follow-Up. Int J Environ Res Public Health. 2022 Dec 25;20(1):328. doi: 10.3390/ijerph20010328. PMID: 36612650; PMCID: PMC9819481. |
| 5 |
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Alcázar González, Alberto |
Alonso JM, Escobar-Peso A, Fernández I, Alcázar A, Marco-Contelles J. Improving the Efficacy of Quinolylnitrones for Ischemic Stroke Therapy, QN4 and QN15 as New Neuroprotective Agents after Oxygen-Glucose Deprivation/Reoxygenation-Induced Neuronal Injury. Pharmaceuticals (Basel). 2022 Nov 7;15(11):1363. doi: 10.3390/ph15111363. PMID: 36355534; PMCID: PMC9697404. |
| 6 |
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Alcázar González, Alberto |
Boria F, Chiva L, Carbonell M, Gutierrez M, Sancho L, Alcazar A, Coronado M, Hernández Gutiérrez A, Zapardiel I. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) predictive score for complete resection in primary cytoreductive surgery. Int J Gynecol Cancer. 2022 Sep 22:ijgc-2022-003883. doi: 10.1136/ijgc-2022-003883. Epub ahead of print. PMID: 36137576. |
| 7 |
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Alcázar González, Alberto |
Fernández-Serra R, Martínez-Alonso E, Alcázar A, Chioua M, Marco-Contelles J, Martínez-Murillo R, Ramos M, Guinea GV, González-Nieto D. Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations. Int J Mol Sci. 2022 Jul 4;23(13):7449. doi: 10.3390/ijms23137449. PMID: 35806455; PMCID: PMC9266990. |
| 8 |
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Alcázar González, Alberto |
Martínez-Alonso E, Escobar-Peso A, Aliena-Valero A, Torregrosa G, Chioua M, Fernández-Serra R, González-Nieto D, Ouahid Y, Salom JB, Masjuan J, Marco-Contelles J, Alcázar A. Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke. Antioxidants (Basel). 2022 Jun 16;11(6):1186. doi: 10.3390/antiox11061186. PMID: 35740081; PMCID: PMC9220178. |
| 9 |
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Alcázar González, Alberto |
Carpio-Escalona LV, Fernández-Lozano C, Peracho L, Martínez-Alonso E, Rita CG, Martínez-Botas J, Alcázar A, de la Hoz Caballer B. Two New Allergens in Watermelon (Citrullus lanatus) Allergy. J Investig Allergol Clin Immunol. 2023 Feb 17;33(1):59-61. doi: 10.18176/jiaci.0804. Epub 2022 Mar 2. PMID: 35234643. |
| 10 |
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Alcázar González, Alberto |
Martínez-Alonso E, Guerra-Pérez N, Escobar-Peso A, Peracho L, Vera-Lechuga R, Cruz-Culebras A, Masjuan J, Alcázar A. Phosphorylation of Eukaryotic Initiation Factor 4G1 (eIF4G1) at Ser1147 Is Specific for eIF4G1 Bound to eIF4E in Delayed Neuronal Death after Ischemia. Int J Mol Sci. 2022 Feb 6;23(3):1830. doi: 10.3390/ijms23031830. PMID: 35163752; PMCID: PMC8836865. |
| 11 |
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Alcázar González, Alberto |
Ferraris Q, Alcazar A, Qian MC. Profiling polar lipids in whey protein phospholipid concentrate by LC-HRMS/MS. Food Chem. 2022 Apr 16;374:131495. doi: 10.1016/j.foodchem.2021.131495. Epub 2021 Oct 28. PMID: 34776307. |
| 12 |
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Alcázar González, Alberto |
Martínez-Alonso E, Guerra-Pérez N, Escobar-Peso A, Regidor I, Masjuan J, Alcázar A. Differential Association of 4E-BP2-Interacting Proteins Is Related to Selective Delayed Neuronal Death after Ischemia. Int J Mol Sci. 2021 Sep 25;22(19):10327. doi: 10.3390/ijms221910327. PMID: 34638676; PMCID: PMC8509075. |
| 13 |
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Alcázar González, Alberto |
Alonso JM, Escobar-Peso A, Palomino-Antolín A, Diez-Iriepa D, Chioua M, Martínez-Alonso E, Iriepa I, Egea J, Alcázar A, Marco-Contelles J. Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer's Disease. Pharmaceuticals (Basel). 2021 Aug 27;14(9):861. doi: 10.3390/ph14090861. PMID: 34577561; PMCID: PMC8465398. |
| 14 |
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Alcázar González, Alberto |
Medina N, Alastruey-Izquierdo A, Bonilla O, Ortíz B, Gamboa O, Salazar LR, Mercado D, Pérez JC, Denning DW, Arathoon E, Rodriguez-Tudela JL; Fungired. Impact of the COVID-19 pandemic on HIV care in Guatemala. Int J Infect Dis. 2021 Jul;108:422-427. doi: 10.1016/j.ijid.2021.06.011. Epub 2021 Jun 10. PMID: 34119676; PMCID: PMC8191308. |
| 15 |
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Alcázar González, Alberto |
Carrón-Herrero A, Fernández-Lozano C, Peracho L, Martínez-Alonso E, Alcázar A, Martínez-Botas J, de-La-Hoz-Caballer B, González-De-Olano D. Custard Apple Allergy With Glycosyltransferase as the Culprit Allergen. J Investig Allergol Clin Immunol. 2021 Feb 21;32(1):73-74. doi: 10.18176/jiaci.0711. Epub 2021 May 28. PMID: 34045178. |
| 16 |
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Alcázar González, Alberto |
Suñé CH, López CC, López PM, Senosiain OG, Escribano MDR, Poyatos JV, Barceló LH, Alcázar ÀR, Carrera-Burgaya A, De la Torre FR, Martínez-Piñeiro A, Cabezas EA. The sternohyoid muscle flap for new dynamic facial reanimation technique: Anatomical study and clinical results. J Plast Reconstr Aesthet Surg. 2021 Nov;74(11):3040-3047. doi: 10.1016/j.bjps.2021.03.085. Epub 2021 Apr 20. PMID: 34020902. |
| 17 |
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Alcázar González, Alberto |
Jakobsen JÅ, Quattrocchi CC, Müller FHH, Outteryck O, Alcázar A, Reith W, Fraga P, Panebianco V, Sampedro A, Pietura R. Patterns of use, effectiveness and safety of gadolinium contrast agents: a European prospective cross-sectional multicentre observational study. BMC Med Imaging. 2021 Apr 20;21(1):74. doi: 10.1186/s12880-021-00600-9. PMID: 33879075; PMCID: PMC8056663. |
| 18 |
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Alcázar González, Alberto |
Martínez-Alonso E, Alcázar P, Camafeita E, Fernández-Lucas M, Ruíz-Roso G, Alcázar A. Proteomic analysis of plasma proteins of high-flux haemodialysis and on-line haemodiafiltration patients reveals differences in transthyretin levels related with anaemia. Sci Rep. 2020 Sep 29;10(1):16029. doi: 10.1038/s41598-020-72104-5. PMID: 32994444; PMCID: PMC7524835. |
| 19 |
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Alcázar González, Alberto |
Fernández-Serra R, Martínez-Alonso E, Alcázar A, Chioua M, Marco-Contelles J, Martínez-Murillo R, Ramos M, Guinea GV, González-Nieto D. Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations. Int J Mol Sci. 2022 Jul 4;23(13):7449. doi: 10.3390/ijms23137449. PMID: 35806455; PMCID: PMC9266990. |
| 20 |
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Alcázar González, Alberto |
Chioua M, Sucunza D, Soriano E, Hadjipavlou-Litina D, Alcázar A, Ayuso I, Oset-Gasque MJ, González MP, Monjas L, Rodríguez-Franco MI, Marco-Contelles J, Samadi A. Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties. J Med Chem. 2012 Jan 12;55(1):153-68. doi: 10.1021/jm201105a. Epub 2011 Dec 21. PMID: 22126405. |
| 21 |
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Alcázar González, Alberto |
Ayuso MI, Martínez-Alonso E, Cid C, Alonso de Leciñana M, Alcázar A. The translational repressor eIF4E-binding protein 2 (4E-BP2) correlates with selective delayed neuronal death after ischemia. J Cereb Blood Flow Metab. 2013 Aug;33(8):1173-81. doi: 10.1038/jcbfm.2013.60. Epub 2013 Apr 17. PMID: 23591646; PMCID: PMC3734765. |
| 22 |
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Alcázar González, Alberto |
Ayuso MI, Martinez-Alonso E, Salvador N, Bonova P, Regidor I, Alcázar A. Dissociation of eIF4E-binding protein 2 (4E-BP2) from eIF4E independent of Thr37/Thr46 phosphorylation in the ischemic stress response. PLoS One. 2015 Mar 30;10(3):e0121958. doi: 10.1371/journal.pone.0121958. PMID: 25822952; PMCID: PMC4379021. |
| 23 |
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Alcázar González, Alberto |
Ayuso MI, Chioua M, Martínez-Alonso E, Soriano E, Montaner J, Masjuán J, Hadjipavlou-Litina DJ, Marco-Contelles J, Alcázar A. CholesteroNitrones for Stroke. J Med Chem. 2015 Aug 27;58(16):6704-9. doi: 10.1021/acs.jmedchem.5b00755. Epub 2015 Aug 13. PMID: 26241908. |
| 24 |
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Angulo Frutos, Javier |
Angulo J, Yang M, Rovira A, Davies PR, Torremorell M. Infection dynamics and incidence of wild-type porcine reproductive and respiratory syndrome virus in growing pig herds in the U.S. Midwest. Prev Vet Med. 2023 Jul 13;217:105976. doi: 10.1016/j.prevetmed.2023.105976. Epub ahead of print. PMID: 37467679. |
| 25 |
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Angulo Frutos, Javier |
Olivencia MA, Gil de Biedma-Elduayen L, Giménez-Gómez P, Barreira B, Fernández A, Angulo J, Colado MI, O'Shea E, Perez-Vizcaino F. Oxidized soluble guanylyl cyclase causes erectile dysfunction in alcoholic mice. Br J Pharmacol. 2023 Apr 6. doi: 10.1111/bph.16087. Epub ahead of print. PMID: 37021655. |
| 26 |
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Angulo Frutos, Javier |
El Assar M, García-Rojo E, Sevilleja-Ortiz A, Sánchez-Ferrer A, Fernández A, García-Gómez B, Romero-Otero J, Rodríguez-Mañas L, Angulo J. Functional Role of STIM-1 and Orai1 in Human Microvascular Aging. Cells. 2022 Nov 18;11(22):3675. doi: 10.3390/cells11223675. PMID: 36429103; PMCID: PMC9688234. |
| 27 |
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Angulo Frutos, Javier |
Balderas C, Angulo J, Sevilleja-Ortiz A, Peiró C, Vallejo S, Dongil P, Ancos B, Sánchez-Moreno C. Onion and Apple Functional Ingredients Intake Improves Antioxidant and Inflammatory Status and Vascular Injury in Obese Zucker Rats. Antioxidants (Basel). 2022 Sep 29;11(10):1953. doi: 10.3390/antiox11101953. PMID: 36290676; PMCID: PMC9598408. |
| 28 |
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Angulo Frutos, Javier |
El Assar M, Álvarez-Bustos A, Sosa P, Angulo J, Rodríguez-Mañas L. Effect of Physical Activity/Exercise on Oxidative Stress and Inflammation in Muscle and Vascular Aging. Int J Mol Sci. 2022 Aug 5;23(15):8713. doi: 10.3390/ijms23158713. PMID: 35955849; PMCID: PMC9369066. |
| 29 |
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Angulo Frutos, Javier |
Sevilleja-Ortiz A, El Assar M, García-Rojo E, García-Gómez B, Fernández A, Sánchez-Ferrer A, La Fuente JM, Romero-Otero J, Rodríguez-Mañas L, Angulo J. Ageing-induced hypercontractility is related to functional enhancement of STIM/Orai and upregulation of Orai 3 in rat and human penile tissue. Mech Ageing Dev. 2021 Dec;200:111590. doi: 10.1016/j.mad.2021.111590. Epub 2021 Oct 23. PMID: 34699858. |
| 30 |
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Angulo Frutos, Javier |
Fernández-Pascual E, González-García FJ, Angulo J, Cerezo E, Quintana LM, Turo J, Martínez-Ballesteros C, Carballido J, Martínez-Salamanca JI. Optimizing collagenase Clostridium histolyticum therapy for Peyronie's disease using a novel approach with percutaneous needle tunnelling. BJU Int. 2019 Dec;124(6):1055-1062. doi: 10.1111/bju.14784. Epub 2019 Jun 9. PMID: 31033130. |
| 31 |
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Baquero Valls, Pablo |
Martínez-Martínez D, Toledo Lobo MV, Baquero P, Ropero S, Angulo JC, Chiloeches A, Lasa M. Downregulation of Snail by DUSP1 Impairs Cell Migration and Invasion through the Inactivation of JNK and ERK and Is Useful as a Predictive Factor in the Prognosis of Prostate Cancer. Cancers (Basel). 2021 Mar 8;13(5):1158. doi: 10.3390/cancers13051158. PMID: 33800291; PMCID: PMC7962644. |
| 32 |
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Baquero Valls, Pablo |
Baquero P, Jiménez-Mora E, Santos A, Lasa M, Chiloeches A. TGFβ induces epithelial-mesenchymal transition of thyroid cancer cells by both the BRAF/MEK/ERK and Src/FAK pathways. Mol Carcinog. 2016 Nov;55(11):1639-1654. doi: 10.1002/mc.22415. Epub 2015 Sep 21. PMID: 26392228. |
| 33 |
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Baquero Valls, Pablo |
Jiménez-Mora E, Gallego B, Díaz-Gago S, Lasa M, Baquero P, Chiloeches A. V600EBRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells. Int J Mol Sci. 2021 Jun 3;22(11):6033. doi: 10.3390/ijms22116033. PMID: 34204950; PMCID: PMC8199856. |
| 34 |
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Baquero Valls, Pablo |
Baquero P, Sánchez-Hernández I, Jiménez-Mora E, Orgaz JL, Jiménez B, Chiloeches A. (V600E)BRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism. Cancer Lett. 2013 Jul 10;335(1):232-41. doi: 10.1016/j.canlet.2013.02.033. Epub 2013 Feb 19. PMID: 23435375. |
| 35 |
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Baquero Valls, Pablo |
Sánchez-Hernández I, Baquero P, Calleros L, Chiloeches A. Dual inhibition of (V600E)BRAF and the PI3K/AKT/mTOR pathway cooperates to induce apoptosis in melanoma cells through a MEK-independent mechanism. Cancer Lett. 2012 Jan 28;314(2):244-55. doi: 10.1016/j.canlet.2011.09.037. Epub 2011 Oct 8. PMID: 22056813. |
| 36 |
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Baquero Valls, Pablo |
Calleros L, Sánchez-Hernández I, Baquero P, Toro MJ, Chiloeches A. Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells. Carcinogenesis. 2009 Oct;30(10):1670-7. doi: 10.1093/carcin/bgp188. Epub 2009 Aug 20. PMID: 19700418. |
| 37 |
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Baquero Valls, Pablo |
Mitchell R, Hopcroft LEM, Baquero P, Allan EK, Hewit K, James D, Hamilton G, Mukhopadhyay A, O'Prey J, Hair A, Melo JV, Chan E, Ryan KM, Maguer-Satta V, Druker BJ, Clark RE, Mitra S, Herzyk P, Nicolini FE, Salomoni P, Shanks E, Calabretta B, Holyoake TL, Helgason GV. Targeting BCR-ABL-Independent TKI Resistance in Chronic Myeloid Leukemia by mTOR and Autophagy Inhibition. J Natl Cancer Inst. 2018 May 1;110(5):467-478. doi: 10.1093/jnci/djx236. PMID: 29165716; PMCID: PMC5946859. |
| 38 |
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Baquero Valls, Pablo |
Fernández-Barral A, Orgaz JL, Baquero P, Ali Z, Moreno A, Tiana M, Gómez V, Riveiro-Falkenbach E, Cañadas C, Zazo S, Bertolotto C, Davidson I, Rodríguez-Peralto JL, Palmero I, Rojo F, Jensen LD, del Peso L, Jiménez B. Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma. Neoplasia. 2014 Jun;16(6):529-42. doi: 10.1016/j.neo.2014.06.001. Epub 2014 Jul 13. PMID: 25030625; PMCID: PMC4198745. |
| 39 |
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Baquero Valls, Pablo |
Baquero P, Dawson A, Mukhopadhyay A, Kuntz EM, Mitchell R, Olivares O, Ianniciello A, Scott MT, Dunn K, Nicastri MC, Winkler JD, Michie AM, Ryan KM, Halsey C, Gottlieb E, Keaney EP, Murphy LO, Amaravadi RK, Holyoake TL, Helgason GV. Targeting quiescent leukemic stem cells using second generation autophagy inhibitors. Leukemia. 2019 Apr;33(4):981-994. doi: 10.1038/s41375-018-0252-4. Epub 2018 Sep 5. PMID: 30185934; PMCID: PMC6292500. |
| 40 |
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Baquero Valls, Pablo |
Karvela M, Baquero P, Kuntz EM, Mukhopadhyay A, Mitchell R, Allan EK, Chan E, Kranc KR, Calabretta B, Salomoni P, Gottlieb E, Holyoake TL, Helgason GV. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016 Jun 2;12(6):936-48. doi: 10.1080/15548627.2016.1162359. Epub 2016 May 11. PMID: 27168493; PMCID: PMC4922442. |
| 41 |
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Blanco Aparicio, Carmen |
González-Muñoz T, Di Giannatale A, Garcia-Silva S, Santos V, Sanchez-Redondo S, Savini C, Graña-Castro O, Blanco-Aparicio C, Fischer S, De Wever O, Creus-Bachiller E, Ortega-Bertran S, Pisapia DJ, Rodríguez-Peralto JL, Fernández-Rodríguez J, Romagosa C, Alaggio R, Benassi MS, Pazzaglia L, Scotlandi K, Ratner N, Yohay K, Theuer CP, Peinado H. Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis. Clin Cancer Res. 2023 Jul 11:CCR-22-2462. doi: 10.1158/1078-0432.CCR-22-2462. Epub ahead of print. PMID: 37432984. |
| 42 |
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Blanco Aparicio, Carmen |
Jimenez L, Amenabar C, Mayoral-Varo V, Mackenzie TA, Ramos MC, Silva A, Calissi G, Grenho I, Blanco-Aparicio C, Pastor J, Megías D, Ferreira BI, Link W. mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity. Molecules. 2022 Aug 24;27(17):5414. doi: 10.3390/molecules27175414. PMID: 36080182; PMCID: PMC9457944. |
| 43 |
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Blanco Aparicio, Carmen |
Jimenez L, Silva A, Calissi G, Grenho I, Monteiro R, Mayoral-Varo V, Blanco-Aparicio C, Pastor J, Bustos V, Bracher F, Megías D, Ferreira BI, Link W. Screening Health-Promoting Compounds for Their Capacity to Induce the Activity of FOXO3. J Gerontol A Biol Sci Med Sci. 2022 Aug 12;77(8):1485-1493. doi: 10.1093/gerona/glab265. PMID: 34508571; PMCID: PMC9373959. |
| 44 |
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Blanco Aparicio, Carmen |
Baquero JM, Marchena-Perea E, Mirabet R, Torres-Ruiz R, Blanco-Aparicio C, Rodríguez-Perales S, Helleday T, Benítez-Buelga C, Benítez J, Osorio A. OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells. Front Oncol. 2022 May 10;12:888810. doi: 10.3389/fonc.2022.888810. PMID: 35619904; PMCID: PMC9127384. |
| 45 |
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Blanco Aparicio, Carmen |
Alvarez RM, García AB, Riesco-Fagundo C, Martín JI, Varela C, Rodríguez Hergueta A, González Cantalapiedra E, Oyarzabal J, Di Geronimo B, Lorenzo M, Albarrán MI, Cebriá A, Cebrián D, Martínez-González S, Blanco-Aparicio C, Pastor J. Corrigendum to <' Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors' [Eur. J. Med. Chem. 211 (2021), 113109]. Eur J Med Chem. 2021 Nov 15;224:113703. doi: 10.1016/j.ejmech.2021.113703. Epub 2021 Jul 17. Erratum for: Eur J Med Chem. 2021 Feb 5;211:113109. PMID: 34284231. |
| 46 |
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Blanco Aparicio, Carmen |
Martínez-González S, Alvarez RM, Martín JI, García AB, Riesco-Fagundo C, Varela C, Rodríguez Hergueta A, González Cantalapiedra E, Albarrán MI, Gómez-Casero E, Cebriá A, Aguirre E, Ajenjo N, Cebrián D, Di Geronimo B, Cunningham D, O'Neill M, Dave HPG, Blanco-Aparicio C, Pastor J. Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors. ACS Med Chem Lett. 2021 Nov 2;12(11):1794-1801. doi: 10.1021/acsmedchemlett.1c00412. PMID: 34795869; PMCID: PMC8591745. |
| 47 |
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Blanco Aparicio, Carmen |
Moore G, Lightner C, Elbai S, Brady L, Nicholson S, Ryan R, O'Sullivan KE, O'Byrne KJ, Blanco-Aparicio C, Cuffe S, O'Neill M, Heavey S, Finn SP, Gately K. Co-Targeting PIM Kinase and PI3K/mTOR in NSCLC. Cancers (Basel). 2021 Apr 29;13(9):2139. doi: 10.3390/cancers13092139. PMID: 33946744; PMCID: PMC8125027. |
| 48 |
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Blanco Aparicio, Carmen |
Álvarez RM, García AB, Riesco-Fagundo C, Martín JI, Varela C, Rodríguez Hergueta A, González Cantalapiedra E, Oyarzabal J, Di Geronimo B, Lorenzo M, Albarrán MI, Cebriá A, Cebrián D, Martínez-González S, Blanco-Aparicio C, Pastor J. Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors. Eur J Med Chem. 2021 Feb 5;211:113109. doi: 10.1016/j.ejmech.2020.113109. Epub 2020 Dec 18. Erratum in: Eur J Med Chem. 2021 Nov 15;224:113703. PMID: 33360802. |
| 49 |
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Blanco Aparicio, Carmen |
Lynch CJ, Bernad R, Martínez-Val A, Shahbazi MN, Nóbrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Ginés L, Alcazar N, Graña-Castro O, Gómez-Lopez G, Aksoy I, Muñoz-Martín M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Muñoz J, Zernicka-Goetz M, Serrano M. Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases. Nat Cell Biol. 2020 Oct;22(10):1223-1238. doi: 10.1038/s41556-020-0573-1. Epub 2020 Sep 28. PMID: 32989249. |
| 50 |
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Busto Durán, Rebeca |
Soto-Huelin B, Babiy B, Pastor O, Díaz-García M, Toledano-Zaragoza A, Frutos MD, Espín JC, Tomás-Barberán FA, Busto R, Ledesma MD. Ellagic acid and its metabolites urolithins A/B ameliorate most common disease phenotypes in cellular and mouse models for lysosomal storage disorders by enhancing extracellular vesicle secretion. Neurobiol Dis. 2023 Jun 15;182:106141. doi: 10.1016/j.nbd.2023.106141. Epub 2023 Apr 28. PMID: 37121555. |
| 51 |
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Busto Durán, Rebeca |
Frutos MF, Pardo-Marqués V, Torrecilla-Parra M, Rada P, Pérez-García A, Martín-Martín Y, de la Peña G, Gómez A, Toledano-Zaragoza A, Gómez-Coronado D, Casarejos MJ, Solís JM, Rotllan N, Pastor Ó, Ledesma MD, Valverde ÁM, Busto R, Ramírez CM. "MiR-7 controls cholesterol biosynthesis through posttranscriptional regulation of DHCR24 expression". Biochim Biophys Acta Gene Regul Mech. 2023 Jun;1866(2):194938. doi: 10.1016/j.bbagrm.2023.194938. Epub 2023 Apr 21. PMID: 37086967. |
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Babiy B, Ramos-Molina B, Ocaña L, Sacristán S, Burgos-Santamaría D, Martínez-Botas J, Busto R, Perna C, Frutos MD, Albillos A, Pastor Ó. Dihydrosphingolipids are associated with steatosis and increased fibrosis damage in non-alcoholic fatty liver disease. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Jul;1868(7):159318. doi: 10.1016/j.bbalip.2023.159318. Epub 2023 Apr 12. PMID: 37059386. |
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Aranda JF, Pérez-García A, Torrecilla-Parra M, Fernández-de Frutos M, Martín-Martín Y, Mateos-Gómez PA, Pardo-Marqués V, Busto R, Ramírez CM. Role of miR-199a-5p in the post-transcriptional regulation of ABCA1 in response to hypoxia in peritoneal macrophages. Front Cardiovasc Med. 2022 Nov 3;9:994080. doi: 10.3389/fcvm.2022.994080. PMID: 36407436; PMCID: PMC9669644. |
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Del Pozo-Acebo L, López de Las Hazas MC, Tomé-Carneiro J, Del Saz-Lara A, Gil-Zamorano J, Balaguer L, Chapado LA, Busto R, Visioli F, Dávalos A. Therapeutic potential of broccoli-derived extracellular vesicles as nanocarriers of exogenous miRNAs. Pharmacol Res. 2022 Nov;185:106472. doi: 10.1016/j.phrs.2022.106472. Epub 2022 Sep 28. PMID: 36182038. |
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Martín-Martín Y, Pérez-García A, Torrecilla-Parra M, Fernández-de Frutos M, Pardo-Marqués V, Casarejos MJ, Busto R, Ramírez CM. New Insights on the Regulation of the Insulin-Degrading Enzyme: Role of microRNAs and RBPs. Cells. 2022 Aug 16;11(16):2538. doi: 10.3390/cells11162538. PMID: 36010613; PMCID: PMC9406717. |
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Molina YL, García-Seisdedos D, Babiy B, Lerma M, Martínez-Botas J, Casarejos MJ, Vallejo MT, Gómez-Coronado D, Lasunción MA, Pastor Ó, Busto R. Rottlerin Stimulates Exosome/Microvesicle Release Via the Increase of Ceramide Levels Mediated by Ampk in an In Vitro Model of Intracellular Lipid Accumulation. Biomedicines. 2022 Jun 3;10(6):1316. doi: 10.3390/biomedicines10061316. PMID: 35740338; PMCID: PMC9219951. |
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Abuobeid R, Sánchez-Marco J, Felices MJ, Arnal C, Burillo JC, Lasheras R, Busto R, Lasunción MA, Rodríguez-Yoldi MJ, Martínez-Beamonte R, Osada J. Squalene through Its Post-Squalene Metabolites Is a Modulator of Hepatic Transcriptome in Rabbits. Int J Mol Sci. 2022 Apr 10;23(8):4172. doi: 10.3390/ijms23084172. PMID: 35456988; PMCID: PMC9031321. |
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Martínez-Beamonte R , Sánchez-Marco J , Felices MJ , Barranquero C , Gascón S , Arnal C , Burillo JC , Lasheras R , Busto R , Lasunción MA , Rodríguez-Yoldi MJ , Osada J . Dietary squalene modifies plasma lipoproteins and hepatic cholesterol metabolism in rabbits. Food Funct. 2021 Sep 7;12(17):8141-8153. doi: 10.1039/d0fo01836h. Epub 2021 Jul 22. PMID: 34291245. |
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Fernández-Suárez ME, Daimiel L, Villa-Turégano G, Pavón MV, Busto R, Escolà-Gil JC, Platt FM, Lasunción MA, Martínez-Botas J, Gómez-Coronado D. Selective estrogen receptor modulators (SERMs) affect cholesterol homeostasis through the master regulators SREBP and LXR. Biomed Pharmacother. 2021 Sep;141:111871. doi: 10.1016/j.biopha.2021.111871. Epub 2021 Jul 3. PMID: 34225017. |
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Robles J, Pintado-Berninches L, Boukich I, Escudero B, de Los Rios V, Bartolomé RA, Jaén M, Martín-Regalado Á, Fernandez-Aceñero MJ, Imbaud JI, Casal JI. A prognostic six-gene expression risk-score derived from proteomic profiling of the metastatic colorectal cancer secretome. J Pathol Clin Res. 2022 Nov;8(6):495-508. doi: 10.1002/cjp2.294. Epub 2022 Sep 22. PMID: 36134447; PMCID: PMC9535096. |
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Jaén M, Martín-Regalado Á, Bartolomé RA, Robles J, Casal JI. Interleukin 13 receptor alpha 2 (IL13Rα2): Expression, signaling pathways and therapeutic applications in cancer. Biochim Biophys Acta Rev Cancer. 2022 Sep;1877(5):188802. doi: 10.1016/j.bbcan.2022.188802. Epub 2022 Sep 21. PMID: 36152905. |
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Solís-Fernández G, Montero-Calle A, Martínez-Useros J, López-Janeiro Á, de Los Ríos V, Sanz R, Dziakova J, Milagrosa E, Fernández-Aceñero MJ, Peláez-García A, Casal JI, Hofkens J, Rocha S, Barderas R. Spatial Proteomic Analysis of Isogenic Metastatic Colorectal Cancer Cells Reveals Key Dysregulated Proteins Associated with Lymph Node, Liver, and Lung Metastasis. Cells. 2022 Jan 27;11(3):447. doi: 10.3390/cells11030447. PMID: 35159257; PMCID: PMC8834500. |
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Colomé N, Abian J, Aloria K, Arizmendi JM, Barceló-Batllori S, Braga-Lagache S, Burlet-Schiltz O, Carrascal M, Casal JI, Chicano-Gálvez E, Chiva C, Clemente LF, Elortza F, Estanyol JM, Fernandez-Irigoyen J, Fernández-Puente P, Fidalgo MJ, Froment C, Fuentes M, Fuentes-Almagro C, Gay M, Hainard A, Heller M, Hernández ML, Ibarrola N, Iloro I, Kieselbach T, Lario A, Locard-Paulet M, Marina-Ramírez A, Martín L, Morato-López E, Muñoz J, Navajas R, Odena MA, Odriozola L, de Oliveira E, Paradela A, Pasquarello C, de Los Rios V, Ruiz-Romero C, Sabidó E, Sánchez Del Pino M, Sancho J, Santamaría E, Schaeffer-Reiss C, Schneider J, de la Torre C, Valero ML, Vilaseca M, Wu S, Wu L, Ximénez de Embún P, Canals F, Corrales FJ; ProteoRed-ISCIII; EuPA. Multi-laboratory experiment PME11 for the standardization of phosphoproteome analysis. J Proteomics. 2022 Jan 16;251:104409. doi: 10.1016/j.jprot.2021.104409. Epub 2021 Nov 7. PMID: 34758407. |
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Merlos Rodrigo MA, Buchtelova H, de Los Rios V, Casal JI, Eckschlager T, Hrabeta J, Belhajova M, Heger Z, Adam V. Correction to "Proteomic Signature of Neuroblastoma Cells UKF-NB-4 Reveals Key Role of Lysosomal Sequestration and the Proteasome Complex in Acquiring Chemoresistance to Cisplatin". J Proteome Res. 2022 Jan 7;21(1):295-296. doi: 10.1021/acs.jproteome.1c00853. Epub 2021 Nov 22. Erratum for: J Proteome Res. 2019 Mar 1;18(3):1255-1263. PMID: 34806879. |
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Bartolomé RA, Robles J, Martin-Regalado Á, Pintado-Berninches L, Burdiel M, Jaén M, Aizpurúa C, Imbaud JI, Casal JI. CDH6-activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers. Mol Oncol. 2021 Jul;15(7):1849-1865. doi: 10.1002/1878-0261.12947. Epub 2021 May 2. PMID: 33715292; PMCID: PMC8253092. |
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Jaén M, Bartolomé RA, Aizpurua C, Martin-Regalado Á, Imbaud JI, Casal JI. Inhibition of Liver Metastasis in Colorectal Cancer by Targeting IL-13/IL13Rα2 Binding Site with Specific Monoclonal Antibodies. Cancers (Basel). 2021 Apr 6;13(7):1731. doi: 10.3390/cancers13071731. PMID: 33917458; PMCID: PMC8038733. |
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López-Janeiro Á, Ruz-Caracuel I, Ramón-Patino JL, De Los Ríos V, Villalba Esparza M, Berjón A, Yébenes L, Hernández A, Masetto I, Kadioglu E, Goubert V, Heredia-Soto V, Barderas R, Casal JI, de Andrea CE, Redondo A, Mendiola M, Peláez-García A, Hardisson D. Proteomic Analysis of Low-Grade, Early-Stage Endometrial Carcinoma Reveals New Dysregulated Pathways Associated with Cell Death and Cell Signaling. Cancers (Basel). 2021 Feb 14;13(4):794. doi: 10.3390/cancers13040794. PMID: 33672863; PMCID: PMC7917913. |
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Bartolomé RA, Pintado-Berninches L, Jaén M, de Los Ríos V, Imbaud JI, Casal JI. SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166. Oncogene. 2020 Sep;39(38):6085-6098. doi: 10.1038/s41388-020-01419-4. Epub 2020 Aug 15. PMID: 32801337. |
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Escudero-Paniagua B, Bartolomé RA, Rodríguez S, De Los Ríos V, Pintado L, Jaén M, Lafarga M, Fernández-Aceñero MJ, Casal JI. PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway. Carcinogenesis. 2020 Apr 22;41(2):203-213. doi: 10.1093/carcin/bgz093. PMID: 31095674. |
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Fernández Martínez, Ana Belén |
Bernardo-Bermejo S, Sánchez-López E, Castro-Puyana M, Fernández-Martínez AB, Lucio-Cazaña FJ, Marina ML. Exploring the Metabolic Differences between Cisplatin- and UV Light-Induced Apoptotic Bodies in HK-2 Cells by an Untargeted Metabolomics Approach. Int J Mol Sci. 2023 Apr 14;24(8):7237. doi: 10.3390/ijms24087237. PMID: 37108400; PMCID: PMC10138416. |
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Fernández Martínez, Ana Belén |
Yago-Ibáñez J, Muñoz-Moreno L, Gallego-Tamayo B, Lucio-Cazaña FJ, Fernández-Martínez AB. Prostaglandin transporter PGT as a new pharmacological target in the prevention of inflammatory cytokine-induced injury in renal proximal tubular HK-2 cells. Life Sci. 2023 Jan 15;313:121260. doi: 10.1016/j.lfs.2022.121260. Epub 2022 Dec 5. PMID: 36473541. |
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Fernández Martínez, Ana Belén |
Ramos-Torres Á, Avellanal-Zaballa E, García-Garrido F, Fernández-Martínez AB, Prieto-Castañeda A, Agarrabeitia AR, Bañuelos J, García-Moreno I, Lucio-Cazaña FJ, Ortiz MJ. Mitochondria selective trackers for long-term imaging based on readily accessible neutral BODIPYs. Chem Commun (Camb). 2021 May 27;57(43):5318-5321. doi: 10.1039/d1cc00451d. PMID: 33913453. |
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Fernández Martínez, Ana Belén |
García-Pastor C, Benito-Martínez S, Bosch RJ, Fernández-Martínez AB, Lucio-Cazaña FJ. Intracellular prostaglandin E2 contributes to hypoxia-induced proximal tubular cell death. Sci Rep. 2021 Mar 29;11(1):7047. doi: 10.1038/s41598-021-86219-w. PMID: 33782420; PMCID: PMC8007803. |
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Fernández Martínez, Ana Belén |
Figueroa O, Muñoz-Reyes JA, Rodriguez-Sickert C, Valenzuela N, Pavez P, Ramírez-Herrera O, Pita M, Diaz D, Fernández-Martínez AB, Polo P. Testing strategic pluralism: The roles of attractiveness and competitive abilities to understand conditionality in men's short-term reproductive strategies. PLoS One. 2020 Aug 31;15(8):e0237315. doi: 10.1371/journal.pone.0237315. Erratum in: PLoS One. 2021 Jun 11;16(6):e0253362. PMID: 32866153; PMCID: PMC7458284. |
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Fernández Martínez, Ana Belén |
Yago-Ibáñez J, García-Pastor C, Lucio-Cazaña FJ, Fernández-Martínez AB. Retinoic acid receptor-beta prevents cisplatin-induced proximal tubular cell death. Biochim Biophys Acta Mol Basis Dis. 2020 Jul 1;1866(7):165795. doi: 10.1016/j.bbadis.2020.165795. Epub 2020 Apr 8. PMID: 32278009. |
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Fernández Martínez, Ana Belén |
García-Pastor C, Benito-Martínez S, Moreno-Manzano V, Fernández-Martínez AB, Lucio-Cazaña FJ. Mechanism and Consequences of The Impaired Hif-1α Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose. Sci Rep. 2019 Nov 1;9(1):15868. doi: 10.1038/s41598-019-52310-6. Erratum in: Sci Rep. 2020 May 20;10(1):8642. PMID: 31676796; PMCID: PMC6825166. |
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Fernández Martínez, Ana Belén |
García-Pastor C, Blázquez-Serra R, Bosch RJ, Lucio Cazaña FJ, Fernández-Martínez AB. Apoptosis and cell proliferation in proximal tubular cells exposed to apoptotic bodies. Novel pathophysiological implications in cisplatin-induced renal injury. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2504-2515. doi: 10.1016/j.bbadis.2019.06.008. Epub 2019 Jun 11. PMID: 31195118. |
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Fernández Martínez, Ana Belén |
Madrigal-Martínez A, Constâncio V, Lucio-Cazaña FJ, Fernández-Martínez AB. PROSTAGLANDIN E2 stimulates cancer-related phenotypes in prostate cancer PC3 cells through cyclooxygenase-2. J Cell Physiol. 2019 May;234(5):7548-7559. doi: 10.1002/jcp.27515. Epub 2018 Oct 26. PMID: 30367494. |
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Fernández Martínez, Ana Belén |
Madrigal-Martínez A, Fernández-Martínez AB, Lucio Cazaña FJ. Intracrine prostaglandin E2 pro-tumoral actions in prostate epithelial cells originate from non-canonical pathways. J Cell Physiol. 2018 Apr;233(4):3590-3602. doi: 10.1002/jcp.26220. Epub 2017 Nov 20. PMID: 29154474. |
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García Díez, Marta |
González-Rubio, R.; Latasa Zamalloa, P.; Aginagalde Llorente, A.H.; Peremiquel-Trillas, P.; Ruiz-Montero, R.; Gullón, P.; García Diez, M.; Reques Sastre, L.; Efrain Pantoja Bustillos, P.; Velasco Muñoz, C. et al. Skills for Preventive Medicine and Public Health: Proposal after a comparative and participative approach,Competencias para Medicina Preventiva y Salud Pública: propuestas tras un proceso comparativo y participativo. Educacion Medica. 2019 DOI: 10.1016/j.edumed.2019.09.004 |
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Roel E; García-Díez M; Borrás Bermejo B [Medical errors, the third leading cause of death in the United States?] Journal of Healthcare Quality Research. 2019 DOI: 10.1016/j.jhqr.2019.06.005 |
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Moreno M, García-Sacristán A, Martín ME, González VM. Enzyme-Linked Oligonucleotide Assay (ELONA). Methods Mol Biol. 2023;2570:235-242. doi: 10.1007/978-1-0716-2695-5_18. PMID: 36156787. |
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Vergara-Barberán M, Lerma-García MJ, Simó-Alfonso EF, García-Hernández M, Martín ME, García-Sacristán A, González VM, Herrero-Martínez JM. Selection and characterization of DNA aptamers for highly selective recognition of the major allergen of olive pollen Ole e 1. Anal Chim Acta. 2022 Feb 1;1192:339334. doi: 10.1016/j.aca.2021.339334. Epub 2021 Dec 2. PMID: 35057930. |
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García Sacristán, Ana |
Aira C, Klett-Mingo JI, Ruiz T, Garcia-Sacristán A, Martín-Valls GE, Mateu E, Gómez-Laguna J, Rueda P, González VM, Rodríguez MJ, López L. Development of an antigen Enzyme-Linked AptaSorbent Assay (ELASA) for the detection of swine influenza virus in field samples. Anal Chim Acta. 2021 Oct 9;1181:338933. doi: 10.1016/j.aca.2021.338933. Epub 2021 Aug 9. PMID: 34556218. |
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García Sacristán, Ana |
Pinilla E, Sánchez A, Martínez MP, Muñoz M, García-Sacristán A, Köhler R, Prieto D, Rivera L. Endothelial KCa 1.1 and KCa 3.1 channels mediate rat intrarenal artery endothelium-derived hyperpolarization response. Acta Physiol (Oxf). 2021 Apr;231(4):e13598. doi: 10.1111/apha.13598. Epub 2020 Dec 26. PMID: 33314681. |
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Climent B, Santiago E, Sánchez A, Muñoz-Picos M, Pérez-Vizcaíno F, García-Sacristán A, Rivera L, Prieto D. Metabolic syndrome inhibits store-operated Ca2+ entry and calcium-induced calcium-release mechanism in coronary artery smooth muscle. Biochem Pharmacol. 2020 Dec;182:114222. doi: 10.1016/j.bcp.2020.114222. Epub 2020 Sep 17. PMID: 32949582. |
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Rodríguez C, Contreras C, Sáenz-Medina J, Muñoz M, Corbacho C, Carballido J, García-Sacristán A, Hernandez M, López M, Rivera L, Prieto D. Activation of the AMP-related kinase (AMPK) induces renal vasodilatation and downregulates Nox-derived reactive oxygen species (ROS) generation. Redox Biol. 2020 Jul;34:101575. doi: 10.1016/j.redox.2020.101575. Epub 2020 May 16. PMID: 32470915; PMCID: PMC7256643. |
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Frezza V, Pinto-Díez C, Fernández G, Soto M, Martín ME, García-Sacristán A, González VM. DNA aptamers targeting Leishmania infantum H3 protein as potential diagnostic tools. Anal Chim Acta. 2020 Apr 22;1107:155-163. doi: 10.1016/j.aca.2020.02.012. Epub 2020 Feb 7. PMID: 32200890. |
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Muñoz M, López-Oliva ME, Rodríguez C, Martínez MP, Sáenz-Medina J, Sánchez A, Climent B, Benedito S, García-Sacristán A, Rivera L, Hernández M, Prieto D. Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity. Redox Biol. 2020 Jan;28:101330. doi: 10.1016/j.redox.2019.101330. Epub 2019 Sep 20. PMID: 31563085; PMCID: PMC6812001. |
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Blaha I, López-Oliva ME, Martínez MP, Recio P, Agis-Torres Á, Martínez AC, Benedito S, García-Sacristán A, Prieto D, Fernandes VS, Hernández M. Bladder Dysfunction in an Obese Zucker Rat: The Role of TRPA1 Channels, Oxidative Stress, and Hydrogen Sulfide. Oxid Med Cell Longev. 2019 Aug 20;2019:5641645. doi: 10.1155/2019/5641645. PMID: 31531184; PMCID: PMC6721245. |
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González VM, Martín ME, Fernández G, García-Sacristán A. Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses. Pharmaceuticals (Basel). 2016 Dec 16;9(4):78. doi: 10.3390/ph9040078. PMID: 27999271; PMCID: PMC5198053. |
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Cisneros E, Moraru M, Gómez-Lozano N, Muntasell A, López-Botet M, Vilches C. Haplotype-Based Analysis of KIR-Gene Profiles in a South European Population-Distribution of Standard and Variant Haplotypes, and Identification of Novel Recombinant Structures. Front Immunol. 2020 Mar 17;11:440. doi: 10.3389/fimmu.2020.00440. PMID: 32256494; PMCID: PMC7089957. |
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Ordóñez D, Moraru M, Gómez-Lozano N, Cisneros E, Vilches C. KIR typing by non-sequencing methods: polymerase-chain reaction with sequence-specific primers. Methods Mol Biol. 2012;882:415-30. doi: 10.1007/978-1-61779-842-9_24. PMID: 22665248. |
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Cisneros E, Moraru M, Gómez-Lozano N, López-Botet M, Vilches C. KIR2DL5: An Orphan Inhibitory Receptor Displaying Complex Patterns of Polymorphism and Expression. Front Immunol. 2012 Sep 17;3:289. doi: 10.3389/fimmu.2012.00289. PMID: 23060877; PMCID: PMC3443818. |
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Gómez-Lozano N, de Pablo R, Puente S, Vilches C. Recognition of HLA-G by the NK cell receptor KIR2DL4 is not essential for human reproduction. Eur J Immunol. 2003 Mar;33(3):639-44. doi: 10.1002/eji.200323741. PMID: 12616484. |
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Gumá M, Angulo A, Vilches C, Gómez-Lozano N, Malats N, López-Botet M. Imprint of human cytomegalovirus infection on the NK cell receptor repertoire. Blood. 2004 Dec 1;104(12):3664-71. doi: 10.1182/blood-2004-05-2058. Epub 2004 Aug 10. PMID: 15304389. |
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Gómez-Lozano N, Estefanía E, Williams F, Halfpenny I, Middleton D, Solís R, Vilches C. The silent KIR3DP1 gene (CD158c) is transcribed and might encode a secreted receptor in a minority of humans, in whom the KIR3DP1, KIR2DL4 and KIR3DL1/KIR3DS1 genes are duplicated. Eur J Immunol. 2005 Jan;35(1):16-24. doi: 10.1002/eji.200425493. PMID: 15580659. |
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Estefanía E, Flores R, Gómez-Lozano N, Aguilar H, López-Botet M, Vilches C. Human KIR2DL5 is an inhibitory receptor expressed on the surface of NK and T lymphocyte subsets. J Immunol. 2007 Apr 1;178(7):4402-10. doi: 10.4049/jimmunol.178.7.4402. PMID: 17371997. |
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Cantero M, Millán-Pérez R, Muñez E, Gómez-Lozano N, Anel-Pedroche J, Parra LM, Rodríguez ML, Asensio A. SARS-COV-2 seroprevalence among all healthcare workers in a tertiary hospital in Spain. Infect Dis (Lond). 2022 Jan;54(1):8-15. doi: 10.1080/23744235.2021.1963468. Epub 2021 Aug 23. PMID: 34424122. |
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Cisneros E, Moraru M, Gómez-Lozano N, Muntasell A, López-Botet M, Vilches C. Haplotype-Based Analysis of KIR-Gene Profiles in a South European Population-Distribution of Standard and Variant Haplotypes, and Identification of Novel Recombinant Structures. Front Immunol. 2020 Mar 17;11:440. doi: 10.3389/fimmu.2020.00440. PMID: 32256494; PMCID: PMC7089957. |
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Lozano-Santos C, García-Vela JA, Pérez-Sanz N, Nova-Gurumeta S, Fernandez-Cuevas B, Gomez-Lozano N, Sánchez-Beato M, Sanchez-Godoy P, Bueno JL, Garcia-Marco JA. Biallelic ATM alterations detected at diagnosis identify a subset of treatment-naïve chronic lymphocytic leukemia patients with reduced overall survival similar to patients with p53 deletion. Leuk Lymphoma. 2017 Apr;58(4):859-865. doi: 10.1080/10428194.2016.1213829. Epub 2016 Aug 8. PMID: 27499002. |
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Martin P, Martínez-Velasquez J, Coronado MJ, Krsnik I, Provencio M, Navarro B, Moraru M, Bellas C, Vilches C, Gomez-Lozano N. Association of DDX58 177 C > T polymorphism with decreased risk of Epstein-Barr virus-related nodular sclerosis classical Hodgkin lymphoma. Leuk Lymphoma. 2017 Feb;58(2):438-444. doi: 10.1080/10428194.2016.1190972. Epub 2016 Jun 7. PMID: 27267403. |
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Carrión-Marchante R, Pinto-Díez C, Klett-Mingo JI, Palacios E, Barragán-Usero M, Pérez-Morgado MI, Pascual-Mellado M, Alcalá S, Ruiz-Cañas L, Sainz B Jr, González VM, Martín ME. An Aptamer against MNK1 for Non-Small Cell Lung Cancer Treatment. Pharmaceutics. 2023 Apr 18;15(4):1273. doi: 10.3390/pharmaceutics15041273. PMID: 37111758; PMCID: PMC10146192. |
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Klett-Mingo JI, Pinto-Díez C, Cambronero-Plaza J, Carrión-Marchante R, Barragán-Usero M, Pérez-Morgado MI, Rodríguez-Martín E, Toledo-Lobo MV, González VM, Martín ME. Potential Therapeutic Use of Aptamers against HAT1 in Lung Cancer. Cancers (Basel). 2022 Dec 30;15(1):227. doi: 10.3390/cancers15010227. PMID: 36612223; PMCID: PMC9818519. |
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de Arriba MDC, Fernández G, Chacón-Solano E, Mataix M, Martínez-Santamaría L, Illera N, Carrión-Marchante R, Martín ME, Larcher F, González VM, Del Río M, Carretero M. FPR2 DNA Aptamers for Targeted Therapy of Wound Repair. J Invest Dermatol. 2022 Aug;142(8):2238-2248.e8. doi: 10.1016/j.jid.2021.12.026. Epub 2022 Jan 1. PMID: 34979109. |
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Vergara-Barberán M, Lerma-García MJ, Simó-Alfonso EF, García-Hernández M, Martín ME, García-Sacristán A, González VM, Herrero-Martínez JM. Selection and characterization of DNA aptamers for highly selective recognition of the major allergen of olive pollen Ole e 1. Anal Chim Acta. 2022 Feb 1;1192:339334. doi: 10.1016/j.aca.2021.339334. Epub 2021 Dec 2. PMID: 35057930. |
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Serumula W, Fernandez G, Gonzalez VM, Parboosing R. Anti-HIV Aptamers: Challenges and Prospects. Curr HIV Res. 2022;20(1):7-19. doi: 10.2174/1570162X19666210908114825. PMID: 34503417. |
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Aira C, Klett-Mingo JI, Ruiz T, Garcia-Sacristán A, Martín-Valls GE, Mateu E, Gómez-Laguna J, Rueda P, González VM, Rodríguez MJ, López L. Development of an antigen Enzyme-Linked AptaSorbent Assay (ELASA) for the detection of swine influenza virus in field samples. Anal Chim Acta. 2021 Oct 9;1181:338933. doi: 10.1016/j.aca.2021.338933. Epub 2021 Aug 9. PMID: 34556218. |
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Carrión-Marchante R, Frezza V, Salgado-Figueroa A, Pérez-Morgado MI, Martín ME, González VM. DNA Aptamers against Vaccinia-Related Kinase (VRK) 1 Block Proliferation in MCF7 Breast Cancer Cells. Pharmaceuticals (Basel). 2021 May 17;14(5):473. doi: 10.3390/ph14050473. PMID: 34067799; PMCID: PMC8156982. |
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Quílez C, Cerdeira E, González-Rico J, de Aranda G, López-Donaire ML, Jorcano JL, Velasco D. Evaluation of different methodologies for primary human dermal fibroblast spheroid formation: automation through 3D bioprinting technology. Biomed Mater. 2022 Jul 1;17(5). doi: 10.1088/1748-605X/ac7a7f. PMID: 35724647. |
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Sanz-Horta R, Matesanz A, Jorcano JL, Velasco D, Acedo P, Gallardo A, Reinecke H, Elvira C. Preparation and Characterization of Plasma-Derived Fibrin Hydrogels Modified by Alginate di-Aldehyde. Int J Mol Sci. 2022 Apr 13;23(8):4296. doi: 10.3390/ijms23084296. PMID: 35457113; PMCID: PMC9029004. |
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Montero A, Atienza C, Elvira C, Jorcano JL, Velasco D. Hyaluronic acid-fibrin hydrogels show improved mechanical stability in dermo-epidermal skin substitutes. Mater Sci Eng C Mater Biol Appl. 2021 Sep;128:112352. doi: 10.1016/j.msec.2021.112352. Epub 2021 Jul 31. PMID: 34474900. |
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Stojic M, Ródenas-Rochina J, López-Donaire ML, González de Torre I, González Pérez M, Rodríguez-Cabello JC, Vojtová L, Jorcano JL, Velasco D. Elastin-Plasma Hybrid Hydrogels for Skin Tissue Engineering. Polymers (Basel). 2021 Jun 28;13(13):2114. doi: 10.3390/polym13132114. PMID: 34203144; PMCID: PMC8271496. |
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Peña-Asensio J, Calvo H, Miquel J, Sanz-de-Villalobos E, González-Praetorius A, Torralba M, Larrubia JR. Model to predict on-treatment restoration of functional HBV-specific CD8+ cell response foresees off-treatment HBV control in eAg-negative chronic hepatitis B. Aliment Pharmacol Ther. 2022 Jun;55(12):1545-1559. doi: 10.1111/apt.16850. Epub 2022 Feb 27. PMID: 35224746; PMCID: PMC9305412. |
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Henriquez-Figuereo A, Alcon M, Moreno E, Sanmartín C, Espuelas S, Lucio H, Jiménez-Ruiz A, Plano D. Next generation of selenocyanate and diselenides with upgraded leishmanicidal activity. Bioorg Chem. 2023 Sep;138:106624. doi: 10.1016/j.bioorg.2023.106624. Epub 2023 May 24. PMID: 37295238. |
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de Lucio H, García-Marín J, Sánchez-Alonso P, García-Soriano JC, Toro MÁ, Vaquero JJ, Gago F, Alajarín R, Jiménez-Ruiz A. Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase. Eur J Med Chem. 2022 Jan 5;227:113915. doi: 10.1016/j.ejmech.2021.113915. Epub 2021 Oct 15. PMID: 34695777. |
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Revuelto A, López-Martín I, de Lucio H, García-Soriano JC, Zanda N, de Castro S, Gago F, Jiménez-Ruiz A, Velázquez S, Camarasa MJ. Small Molecule-Peptide Conjugates as Dimerization Inhibitors of Leishmania infantum Trypanothione Disulfide Reductase. Pharmaceuticals (Basel). 2021 Jul 17;14(7):689. doi: 10.3390/ph14070689. PMID: 34358115; PMCID: PMC8308777. |
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Revuelto A, de Lucio H, García-Soriano JC, Sánchez-Murcia PA, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazoles. J Med Chem. 2021 May 13;64(9):6137-6160. doi: 10.1021/acs.jmedchem.1c00206. Epub 2021 May 4. PMID: 33945281; PMCID: PMC8480782. |
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Revuelto A, Ruiz-Santaquiteria M, de Lucio H, Gamo A, Carriles AA, Gutiérrez KJ, Sánchez-Murcia PA, Hermoso JA, Gago F, Camarasa MJ, Jiménez-Ruiz A, Velázquez S. Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase. ACS Infect Dis. 2019 Jun 14;5(6):873-891. doi: 10.1021/acsinfecdis.8b00355. Epub 2019 Apr 23. PMID: 30983322. |
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Díaz M, de Lucio H, Moreno E, Espuelas S, Aydillo C, Jiménez-Ruiz A, Toro MÁ, Gutiérrez KJ, Martínez-Merino V, Cornejo A, Palop JA, Sanmartín C, Plano D. Synthesis and Leishmanicidal Activity of Novel Urea, Thiourea, and Selenourea Derivatives of Diselenides. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02200-18. doi: 10.1128/AAC.02200-18. PMID: 30782984; PMCID: PMC6496061. |
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Bravo A, de Lucio H, Sánchez-Murcia PA, Jiménez-Ruiz A, Petrone PM, Gago F, Cortés Cabrera A. Identification of NEK3 and MOK as novel targets for lithium. Chem Biol Drug Des. 2019 May;93(5):965-969. doi: 10.1111/cbdd.13487. Epub 2019 Feb 12. PMID: 30667602. |
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Ruiz-Santaquiteria M, de Castro S, Toro MA, de Lucio H, Gutiérrez KJ, Sánchez-Murcia PA, Jiménez MÁ, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability. Eur J Med Chem. 2018 Apr 10;149:238-247. doi: 10.1016/j.ejmech.2018.02.071. Epub 2018 Feb 24. PMID: 29501944. |
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de Lucio H, Gamo AM, Ruiz-Santaquiteria M, de Castro S, Sánchez-Murcia PA, Toro MA, Gutiérrez KJ, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides. Eur J Med Chem. 2017 Nov 10;140:615-623. doi: 10.1016/j.ejmech.2017.09.032. Epub 2017 Sep 21. PMID: 29017116. |
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Ruiz-Santaquiteria M, Sánchez-Murcia PA, Toro MA, de Lucio H, Gutiérrez KJ, de Castro S, Carneiro FAC, Gago F, Jiménez-Ruiz A, Camarasa MJ, Velázquez S. First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity. Eur J Med Chem. 2017 Jul 28;135:49-59. doi: 10.1016/j.ejmech.2017.04.020. Epub 2017 Apr 13. PMID: 28431354. |
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Genes CM, de Lucio H, González VM, Sánchez-Murcia PA, Rico E, Gago F, Fasel N, Jiménez-Ruiz A. A functional BH3 domain in an aquaporin from Leishmania infantum. Cell Death Discov. 2016 Jul 4;2:16043. doi: 10.1038/cddiscovery.2016.43. PMID: 27551533; PMCID: PMC4979448. |
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Genes CM, de Lucio H, Sánchez-Murcia PA, Gago F, Jiménez-Ruiz A. Pro-death activity of a BH3 domain in an aquaporin from the protozoan parasite Leishmania. Cell Death Dis. 2016 Jul 28;7(7):e2318. doi: 10.1038/cddis.2016.229. PMID: 27468694; PMCID: PMC4973364. |
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Blasco A, Coronado MJ, Vela P, Martín P, Solano J, Ramil E, Mesquida A, Santos A, Cózar B, Royuela A, García D, Camarzana S, Parra C, Oteo JF, Goicolea J, Bellas C. Prognostic Implications of Neutrophil Extracellular Traps in Coronary Thrombi of Patients with ST-Elevation Myocardial Infarction. Thromb Haemost. 2022 Aug;122(8):1415-1428. doi: 10.1055/a-1709-5271. Epub 2021 Nov 30. PMID: 34847588. |
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Rodríguez M, Alonso-Alonso R, Tomás-Roca L, Rodríguez-Pinilla SM, Manso-Alonso R, Cereceda L, Borregón J, Villaescusa T, Córdoba R, Sánchez-Beato M, Fernández-Miranda I, Betancor I, Bárcena C, García JF, Mollejo M, García-Cosio M, Martin-Acosta P, Climent F, Caballero D, de la Fuente L, Mínguez P, Kessler L, Scholz C, Gualberto A, Mondéjar R, Piris MA. Peripheral T-cell lymphoma: molecular profiling recognizes subclasses and identifies prognostic markers. Blood Adv. 2021 Dec 28;5(24):5588-5598. doi: 10.1182/bloodadvances.2021005171. PMID: 34592752; PMCID: PMC8714715. |
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Pedrosa L, Fernández-Miranda I, Pérez-Callejo D, Quero C, Rodríguez M, Martín-Acosta P, Gómez S, González-Rincón J, Santos A, Tarin C, García JF, García-Arroyo FR, Rueda A, Camacho FI, García-Cosío M, Heredero A, Llanos M, Mollejo M, Piris-Villaespesa M, Gómez-Codina J, Yanguas-Casás N, Sánchez A, Piris MA, Provencio M, Sánchez-Beato M. Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma. Sci Rep. 2021 Jan 21;11(1):1886. doi: 10.1038/s41598-020-80376-0. PMID: 33479306; PMCID: PMC7820010. |
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Blasco A, Coronado MJ, Hernández-Terciado F, Martín P, Royuela A, Ramil E, García D, Goicolea J, Del Trigo M, Ortega J, Escudier JM, Silva L, Bellas C. Assessment of Neutrophil Extracellular Traps in Coronary Thrombus of a Case Series of Patients With COVID-19 and Myocardial Infarction. JAMA Cardiol. 2020 Dec 29;6(4):1–6. doi: 10.1001/jamacardio.2020.7308. Epub ahead of print. PMID: 33372956; PMCID: PMC7772744. |
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Camacho Castañeda FI, Dotor A, Manso R, Martín P, Prieto Pareja E, Palomo Esteban T, García Vela JA, Santonja C, Piris MA, Rodríguez Pinilla SM. Epstein-Barr virus-associated large B-cell lymphoma transformation in marginal zone B-cell lymphoma: a series of four cases. Histopathology. 2020 Jul;77(1):112-122. doi: 10.1111/his.14101. Epub 2020 Jun 12. PMID: 32145092. |
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Martín-Ruiz A, Fiuza-Luces C, Martínez-Martínez E, Arias CF, Gutiérrez L, Ramírez M, Martín-Acosta P, Coronado MJ, Lucia A, Provencio M. Effects of anti-PD-1 immunotherapy on tumor regression: insights from a patient-derived xenograft model. Sci Rep. 2020 Apr 27;10(1):7078. doi: 10.1038/s41598-020-63796-w. PMID: 32341383; PMCID: PMC7184589. |
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Martín-Ruiz A, Fiuza-Luces C, Rincón-Castanedo C, Fernández-Moreno D, Gálvez BG, Martínez-Martínez E, Martín-Acosta P, Coronado MJ, Franco-Luzón L, González-Murillo Á, Ramírez M, Provencio M, Lucia A. Benefits of exercise and immunotherapy in a murine model of human non-small-cell lung carcinoma. Exerc Immunol Rev. 2020;26:100-115. PMID: 32139351. |
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Provencio M, Pérez-Barrios C, Barquin M, Calvo V, Franco F, Sánchez E, Sánchez R, Marsden D, Cristóbal Sánchez J, Martin Acosta P, Laza-Briviesca R, Cruz-Bermúdez A, Romero A. Next-generation sequencing for tumor mutation quantification using liquid biopsies. Clin Chem Lab Med. 2020 Jan 28;58(2):306-313. doi: 10.1515/cclm-2019-0745. PMID: 31469650. |
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Cruz-Bermúdez A, Laza-Briviesca R, Vicente-Blanco RJ, García-Grande A, Coronado MJ, Laine-Menéndez S, Palacios-Zambrano S, Moreno-Villa MR, Ruiz-Valdepeñas AM, Lendinez C, Romero A, Franco F, Calvo V, Alfaro C, Acosta PM, Salas C, Garcia JM, Provencio M. Cisplatin resistance involves a metabolic reprogramming through ROS and PGC-1α in NSCLC which can be overcome by OXPHOS inhibition. Free Radic Biol Med. 2019 May 1;135:167-181. doi: 10.1016/j.freeradbiomed.2019.03.009. Epub 2019 Mar 14. PMID: 30880247. |
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González-Rincón J, Méndez M, Gómez S, García JF, Martín P, Bellas C, Pedrosa L, Rodríguez-Pinilla SM, Camacho FI, Quero C, Pérez-Callejo D, Rueda A, Llanos M, Gómez-Codina J, Piris MA, Montes-Moreno S, Bárcena C, Rodríguez-Abreu D, Menárguez J, de la Cruz-Merino L, Monsalvo S, Parejo C, Royuela A, Kwee I, Cascione L, Arribas A, Bertoni F, Mollejo M, Provencio M, Sánchez-Beato M. Unraveling transformation of follicular lymphoma to diffuse large B-cell lymphoma. PLoS One. 2019 Feb 25;14(2):e0212813. doi: 10.1371/journal.pone.0212813. PMID: 30802265; PMCID: PMC6388933. |
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Cruz-Bermúdez A, Laza-Briviesca R, Vicente-Blanco RJ, García-Grande A, Coronado MJ, Laine-Menéndez S, Alfaro C, Sanchez JC, Franco F, Calvo V, Romero A, Martin-Acosta P, Salas C, Garcia JM, Provencio M. Cancer-associated fibroblasts modify lung cancer metabolism involving ROS and TGF-β signaling. Free Radic Biol Med. 2019 Jan;130:163-173. doi: 10.1016/j.freeradbiomed.2018.10.450. Epub 2018 Nov 1. PMID: 30391585. |
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Santos A, Martín P, Blasco A, Solano J, Cózar B, García D, Goicolea J, Bellas C, Coronado MJ. NETs detection and quantification in paraffin embedded samples using confocal microscopy. Micron. 2018 Nov;114:1-7. doi: 10.1016/j.micron.2018.07.002. Epub 2018 Jul 18. PMID: 30028972. |
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Martin ME. Inhaled aptamer therapy: A hopeful therapy for lung disease. Mol Ther Nucleic Acids. 2023 May 26;32:875-876. doi: 10.1016/j.omtn.2023.05.009. PMID: 37273784; PMCID: PMC10238564. |
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Martín Palma, María Elena |
Carrión-Marchante R, Pinto-Díez C, Klett-Mingo JI, Palacios E, Barragán-Usero M, Pérez-Morgado MI, Pascual-Mellado M, Alcalá S, Ruiz-Cañas L, Sainz B Jr, González VM, Martín ME. An Aptamer against MNK1 for Non-Small Cell Lung Cancer Treatment. Pharmaceutics. 2023 Apr 18;15(4):1273. doi: 10.3390/pharmaceutics15041273. PMID: 37111758; PMCID: PMC10146192. |
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Martín Palma, María Elena |
Moreno M, García-Sacristán A, Martín ME, González VM. Enzyme-Linked Oligonucleotide Assay (ELONA). Methods Mol Biol. 2023;2570:235-242. doi: 10.1007/978-1-0716-2695-5_18. PMID: 36156787. |
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Klett-Mingo JI, Pinto-Díez C, Cambronero-Plaza J, Carrión-Marchante R, Barragán-Usero M, Pérez-Morgado MI, Rodríguez-Martín E, Toledo-Lobo MV, González VM, Martín ME. Potential Therapeutic Use of Aptamers against HAT1 in Lung Cancer. Cancers (Basel). 2022 Dec 30;15(1):227. doi: 10.3390/cancers15010227. PMID: 36612223; PMCID: PMC9818519. |
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de Arriba MDC, Fernández G, Chacón-Solano E, Mataix M, Martínez-Santamaría L, Illera N, Carrión-Marchante R, Martín ME, Larcher F, González VM, Del Río M, Carretero M. FPR2 DNA Aptamers for Targeted Therapy of Wound Repair. J Invest Dermatol. 2022 Aug;142(8):2238-2248.e8. doi: 10.1016/j.jid.2021.12.026. Epub 2022 Jan 1. PMID: 34979109. |
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Martín Palma, María Elena |
Vergara-Barberán M, Lerma-García MJ, Simó-Alfonso EF, García-Hernández M, Martín ME, García-Sacristán A, González VM, Herrero-Martínez JM. Selection and characterization of DNA aptamers for highly selective recognition of the major allergen of olive pollen Ole e 1. Anal Chim Acta. 2022 Feb 1;1192:339334. doi: 10.1016/j.aca.2021.339334. Epub 2021 Dec 2. PMID: 35057930. |
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Martín Palma, María Elena |
Carrión-Marchante R, Frezza V, Salgado-Figueroa A, Pérez-Morgado MI, Martín ME, González VM. DNA Aptamers against Vaccinia-Related Kinase (VRK) 1 Block Proliferation in MCF7 Breast Cancer Cells. Pharmaceuticals (Basel). 2021 May 17;14(5):473. doi: 10.3390/ph14050473. PMID: 34067799; PMCID: PMC8156982. |
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Frezza V, Pinto-Díez C, Fernández G, Soto M, Martín ME, García-Sacristán A, González VM. DNA aptamers targeting Leishmania infantum H3 protein as potential diagnostic tools. Anal Chim Acta. 2020 Apr 22;1107:155-163. doi: 10.1016/j.aca.2020.02.012. Epub 2020 Feb 7. PMID: 32200890. |
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Fernández G, Moraga A, Cuartero MI, García-Culebras A, Peña-Martínez C, Pradillo JM, Hernández-Jiménez M, Sacristán S, Ayuso MI, Gonzalo-Gobernado R, Fernández-López D, Martín ME, Moro MA, González VM, Lizasoain I. TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models. Mol Ther. 2018 Aug 1;26(8):2047-2059. doi: 10.1016/j.ymthe.2018.05.019. Epub 2018 Jun 15. PMID: 29910175; PMCID: PMC6094477. |
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Martín Palma, María Elena |
Chonco L, Fernández G, Kalhapure R, Hernáiz MJ, García-Oliva C, Gonzalez VM, Martín ME, Govender T, Parboosing R. Novel DNA Aptamers Against CCL21 Protein: Characterization and Biomedical Applications for Targeted Drug Delivery to T Cell-Rich Zones. Nucleic Acid Ther. 2018 Aug;28(4):242-251. doi: 10.1089/nat.2017.0689. Epub 2018 May 7. PMID: 29733244. |
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Martínez Fernández, Mónica |
Martinez VG, Munera-Maravilla E, Bernardini A, Rubio C, Suarez-Cabrera C, Segovia C, Lodewijk I, Dueñas M, Martínez-Fernández M, Paramio JM. Epigenetics of Bladder Cancer: Where Biomarkers and Therapeutic Targets Meet. Front Genet. 2019 Nov 18;10:1125. doi: 10.3389/fgene.2019.01125. PMID: 31850055; PMCID: PMC6902278. |
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Suarez-Cabrera C, Estudillo L, Ramón-Gil E, Martínez-Fernández M, Peral J, Rubio C, Lodewijk I, Martín de Bernardo Á, García-Escudero R, Villacampa F, Duarte J, de la Rosa F, Castellano D, Guerrero-Ramos F, Real FX, Malats N, Paramio JM, Dueñas M. BlaDimiR: A Urine-based miRNA Score for Accurate Bladder Cancer Diagnosis and Follow-up. Eur Urol. 2022 Dec;82(6):663-667. doi: 10.1016/j.eururo.2022.08.011. Epub 2022 Sep 6. PMID: 36085102. |
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Segovia C, San José-Enériz E, Munera-Maravilla E, Martínez-Fernández M, Garate L, Miranda E, Vilas-Zornoza A, Lodewijk I, Rubio C, Segrelles C, Valcárcel LV, Rabal O, Casares N, Bernardini A, Suarez-Cabrera C, López-Calderón FF, Fortes P, Casado JA, Dueñas M, Villacampa F, Lasarte JJ, Guerrero-Ramos F, de Velasco G, Oyarzabal J, Castellano D, Agirre X, Prósper F, Paramio JM. Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression. Nat Med. 2019 Jul;25(7):1073-1081. doi: 10.1038/s41591-019-0499-y. Epub 2019 Jul 3. PMID: 31270502. |
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Dueñas M, Pérez-Figueroa A, Oliveira C, Suárez-Cabrera C, Sousa A, Oliveira P, Villacampa F, Paramio JM, Martínez-Fernández M. Gene Expression Analyses in Non Muscle Invasive Bladder Cancer Reveals a Role for Alternative Splicing and Tp53 Status. Sci Rep. 2019 Jul 17;9(1):10362. doi: 10.1038/s41598-019-46652-4. PMID: 31316092; PMCID: PMC6637137. |
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Rubio C, Martínez-Fernández M, Segovia C, Lodewijk I, Suarez-Cabrera C, Segrelles C, López-Calderón F, Munera-Maravilla E, Santos M, Bernardini A, García-Escudero R, Lorz C, Gómez-Rodriguez MJ, de Velasco G, Otero I, Villacampa F, Guerrero-Ramos F, Ruiz S, de la Rosa F, Domínguez-Rodríguez S, Real FX, Malats N, Castellano D, Dueñas M, Paramio JM. CDK4/6 Inhibitor as a Novel Therapeutic Approach for Advanced Bladder Cancer Independently of RB1 Status. Clin Cancer Res. 2019 Jan 1;25(1):390-402. doi: 10.1158/1078-0432.CCR-18-0685. Epub 2018 Sep 21. PMID: 30242024. |
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Martínez VG, Rubio C, Martínez-Fernández M, Segovia C, López-Calderón F, Garín MI, Teijeira A, Munera-Maravilla E, Varas A, Sacedón R, Guerrero F, Villacampa F, de la Rosa F, Castellano D, López-Collazo E, Paramio JM, Vicente Á, Dueñas M. BMP4 Induces M2 Macrophage Polarization and Favors Tumor Progression in Bladder Cancer. Clin Cancer Res. 2017 Dec 1;23(23):7388-7399. doi: 10.1158/1078-0432.CCR-17-1004. Epub 2017 Sep 19. PMID: 28928159. |
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Segovia C, Martínez-Fernández M, Dueñas M, Rubio C, López-Calderón FF, Costa C, Saiz-Ladera C, Fernández-Grajera M, Duarte J, Muñoz HG, de la Rosa F, Villacampa F, Castellano D, Paramio JM. Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer. Oncotarget. 2017 Feb 7;8(6):10531-10542. doi: 10.18632/oncotarget.14453. PMID: 28060766; PMCID: PMC5354678. |
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Martínez-Fernández M, Paramio JM, Dueñas M. RNA Detection in Urine: From RNA Extraction to Good Normalizer Molecules. J Mol Diagn. 2016 Jan;18(1):15-22. doi: 10.1016/j.jmoldx.2015.07.008. Epub 2015 Nov 14. PMID: 26586227. |
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Martínez-Fernández M, Feber A, Dueñas M, Segovia C, Rubio C, Fernandez M, Villacampa F, Duarte J, López-Calderón FF, Gómez-Rodriguez MJ, Castellano D, Rodriguez-Peralto JL, de la Rosa F, Beck S, Paramio JM. Analysis of the Polycomb-related lncRNAs HOTAIR and ANRIL in bladder cancer. Clin Epigenetics. 2015 Oct 8;7:109. doi: 10.1186/s13148-015-0141-x. PMID: 26457124; PMCID: PMC4599691. |
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Scutelnic A, van de Munckhof A, Krzywicka K, van Kammen MS, Lindgren E, Cordonnier C, Kleinig TJ, Field TS, Poli S, Lemmens R, Middeldorp S, Aaron S, Borhani-Haghighi A, Arauz A, Kremer Hovinga JA, Günther A, Putaala J, Wasay M, Conforto AB, de Sousa DA, Jood K, Tatlisumak T, Ferro JM, Coutinho JM, Arnold M, Heldner MR; Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group**. Sex differences in cerebral venous sinus thrombosis after adenoviral vaccination against COVID-19. Eur Stroke J. 2023 Jul 11:23969873231185213. doi: 10.1177/23969873231185213. Epub ahead of print. PMID: 37434312; PMCID: PMC10345391. |
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Ros Castelló V, Sánchez Sánchez A, Natera Villalba E, Gómez López A, Parra P, Rodríguez Jorge F, Buisán Catevilla J, García Barragán N, Masjuan J, Corral I. Spinal cord infarction: aetiology, imaging findings, and prognostic factors in a series of 41 patients. Neurologia (Engl Ed). 2023 Jul-Aug;38(6):391-398. doi: 10.1016/j.nrleng.2020.11.004. Epub 2021 Jun 12. PMID: 34130946. |
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van de Munckhof A, Borhani-Haghighi A, Aaron S, Krzywicka K, van Kammen MS, Cordonnier C, Kleinig TJ, Field TS, Poli S, Lemmens R, Scutelnic A, Lindgren E, Duan J, Arslan Y, van Gorp EC, Kremer Hovinga JA, Günther A, Jood K, Tatlisumak T, Putaala J, Heldner MR, Arnold M, de Sousa DA, Wasay M, Arauz A, Conforto AB, Ferro JM, Coutinho JM; Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group. Cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia in middle-income countries. Int J Stroke. 2023 Jun 30:17474930231182901. doi: 10.1177/17474930231182901. Epub ahead of print. PMID: 37277922. |
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Hernández-Jiménez M, Abad-Santos F, Cotgreave I, Gallego J, Jilma B, Flores A, Jovin TG, Vivancos J, Hernández-Pérez M, Molina CA, Montaner J, Casariego J, Dalsgaard M, Liebeskind DS, Cobo E, Castellanos M, Portela PC, Masjuán J, Moniche F, Tembl JI, Terceño Izaga M, Arenillas JF, Callejas P, Olivot JM, Calviere L, Henon H, Mazighi M, Piñeiro D, Pugliese M, González VM, Moro MA, Garcia-Tornel A, Lizasoain I, Ribo M. Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial. JAMA Neurol. 2023 Jun 20:e231660. doi: 10.1001/jamaneurol.2023.1660. Epub ahead of print. PMID: 37338893; PMCID: PMC10282959. |
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Martínez-Alonso E, Escobar-Peso A, Guerra-Pérez N, Roca M, Masjuan J, Alcázar A. Dihydropyrimidinase-Related Protein 2 Is a New Partner in the Binding between 4E-BP2 and eIF4E Related to Neuronal Death after Cerebral Ischemia. Int J Mol Sci. 2023 May 4;24(9):8246. doi: 10.3390/ijms24098246. PMID: 37175950; PMCID: PMC10179276. |
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Dubey BN, Agustoni E, Böhm R, Kaczmarczyk A, Mangia F, von Arx C, Jenal U, Hiller S, Plaza-Menacho I, Schirmer T. Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1000-1008. doi: 10.1073/pnas.1911427117. Epub 2019 Dec 27. PMID: 31882446; PMCID: PMC6969517. |
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Redaelli S, Plaza-Menacho I, Mologni L. Novel targeted therapeutics for MEN2. Endocr Relat Cancer. 2018 Feb;25(2):T53-T68. doi: 10.1530/ERC-17-0297. PMID: 29348306. |
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Plaza-Menacho I. Structure and function of RET in multiple endocrine neoplasia type 2. Endocr Relat Cancer. 2018 Feb;25(2):T79-T90. doi: 10.1530/ERC-17-0354. Epub 2017 Nov 24. PMID: 29175871. |
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Plaza-Menacho I, Barnouin K, Barry R, Borg A, Orme M, Chauhan R, Mouilleron S, Martínez-Torres RJ, Meier P, McDonald NQ. RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements. Cell Rep. 2016 Dec 20;17(12):3319-3332. doi: 10.1016/j.celrep.2016.11.061. PMID: 28009299; PMCID: PMC5199340. |
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Dubey BN, Lori C, Ozaki S, Fucile G, Plaza-Menacho I, Jenal U, Schirmer T. Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking. Sci Adv. 2016 Sep 16;2(9):e1600823. doi: 10.1126/sciadv.1600823. PMID: 27652341; PMCID: PMC5026420. |
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Plaza-Menacho I, Barnouin K, Goodman K, Martínez-Torres RJ, Borg A, Murray-Rust J, Mouilleron S, Knowles P, McDonald NQ. Oncogenic RET kinase domain mutations perturb the autophosphorylation trajectory by enhancing substrate presentation in trans. Mol Cell. 2014 Mar 6;53(5):738-51. doi: 10.1016/j.molcel.2014.01.015. Epub 2014 Feb 20. PMID: 24560924; PMCID: PMC3988870. |
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Mologni L, Redaelli S, Morandi A, Plaza-Menacho I, Gambacorti-Passerini C. Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase. Mol Cell Endocrinol. 2013 Sep 5;377(1-2):1-6. doi: 10.1016/j.mce.2013.06.025. Epub 2013 Jun 27. PMID: 23811235. |
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Morandi A, Martin LA, Gao Q, Pancholi S, Mackay A, Robertson D, Zvelebil M, Dowsett M, Plaza-Menacho I, Isacke CM. GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors. Cancer Res. 2013 Jun 15;73(12):3783-95. doi: 10.1158/0008-5472.CAN-12-4265. Epub 2013 May 6. PMID: 23650283; PMCID: PMC3686594. |
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de Frutos S, Griera M, Lavín-López MDP, Martínez-Rovira M, Martínez-Rovira JA, Rodríguez-Puyol M, Rodríguez-Puyol D. A new graphene-based nanomaterial increases lipolysis and reduces body weight gain through integrin linked kinase (ILK). Biomater Sci. 2023 Jul 12;11(14):4916-4929. doi: 10.1039/d2bm01791a. PMID: 37306667. |
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Martinez VR, Martins Lima A, Stergiopulos N, Velez Rueda JO, Islas MS, Griera M, Calleros L, Rodriguez Puyol M, Jaquenod de Giusti C, Portiansky EL, Ferrer EG, De Giusti V, Williams PAM. Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy. Eur J Pharmacol. 2023 May 5;946:175654. doi: 10.1016/j.ejphar.2023.175654. Epub 2023 Mar 15. PMID: 36930883. |
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Campillo S, Bohorquez L, Gutiérrez-Calabrés E, García-Ayuso D, Miguel V, Griera M, Calle Y, de Frutos S, Rodríguez-Puyol M, Rodríguez-Puyol D, Calleros L. Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation. Exp Mol Med. 2022 Mar;54(3):226-238. doi: 10.1038/s12276-022-00738-8. Epub 2022 Mar 4. PMID: 35246616; PMCID: PMC8980039. |
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de Frutos S, Griera M, Hatem-Vaquero M, Campillo S, Gutiérrez-Calabres E, García-Ayuso D, Pardo M, Calleros L, Rodríguez-Puyol M, Rodríguez-Puyol D. The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo. Cell Biosci. 2022 Jan 28;12(1):10. doi: 10.1186/s13578-022-00746-1. PMID: 35090553; PMCID: PMC8796419. |
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Garcia-Marin J, Griera-Merino M, Matamoros-Recio A, de Frutos S, Rodríguez-Puyol M, Alajarín R, Vaquero JJ, Rodríguez-Puyol D. Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein-Protein Interaction with α-Parvin. ACS Med Chem Lett. 2021 Jul 15;12(11):1656-1662. doi: 10.1021/acsmedchemlett.1c00183. PMID: 34790291; PMCID: PMC8591738. |
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García-Marín J, Griera M, Alajarín R, Rodríguez-Puyol M, Rodríguez-Puyol D, Vaquero JJ. A Computer-Driven Scaffold-Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2-a]quinoxaline Core. ChemMedChem. 2021 Sep 16;16(18):2895-2906. doi: 10.1002/cmdc.202100338. Epub 2021 Jul 19. PMID: 34137509; PMCID: PMC8518816. |
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Sánchez-Alonso P, Griera M, García-Marín J, Rodríguez-Puyol M, Alajarín R, Vaquero JJ, Rodríguez-Puyol D. Pyrrolo[1,2-a]quinoxal-5-inium salts and 4,5-dihydropyrrolo[1,2-a]quinoxalines: Synthesis, activity and computational docking for protein tyrosine phosphatase 1B. Bioorg Med Chem. 2021 Aug 15;44:116295. doi: 10.1016/j.bmc.2021.116295. Epub 2021 Jul 3. PMID: 34246920. |
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García-Marín J, Griera M, Sánchez-Alonso P, Di Geronimo B, Mendicuti F, Rodríguez-Puyol M, Alajarín R, de Pascual-Teresa B, Vaquero JJ, Rodríguez-Puyol D. Pyrrolo[1,2-a]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B. ChemMedChem. 2020 Oct 5;15(19):1788-1801. doi: 10.1002/cmdc.202000446. Epub 2020 Sep 10. PMID: 32909701. |
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Hatem-Vaquero M, Griera M, Garcia-Ayuso D, Campillo S, Bohorquez L, Calleros L, Rodriguez-Puyol D, Rodriguez-Puyol M, de Frutos S. Integrin Linked Kinase (ILK) Downregulation as an Early Event During the Development of Metabolic Alterations in a Short-Term High Fat Diet Mice Model. Cell Physiol Biochem. 2020 Jan 24;54(1):71-87. doi: 10.33594/000000206. PMID: 31972071. |
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de Frutos S, Luengo A, García-Jérez A, Hatem-Vaquero M, Griera M, O'Valle F, Rodríguez-Puyol M, Rodríguez-Puyol D, Calleros L. Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression. Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1284-1297. doi: 10.1016/j.bbadis.2019.01.024. Epub 2019 Feb 3. PMID: 30726718. |
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González-Morena JM, Sánchez-Gómez FJ, Vida Y, Pérez-Inestrosa E, Salas M, Montañez MI, Altomare A, Aldini G, Pajares MA, Pérez-Sala D. Amoxicillin Haptenation of α-Enolase is Modulated by Active Site Occupancy and Acetylation. Front Pharmacol. 2022 Jan 13;12:807742. doi: 10.3389/fphar.2021.807742. PMID: 35095517; PMCID: PMC8793629. |
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Castellucci R, Linares Quevedo AI, Sánchez Gómez FJ, Cogollos Acuña I, Salmerón Béliz I, Muñoz Fernández de Legaría M, Salinas S, Martínez Piñeiro L. A non-randomized prospective study on the diagnostic performance of perineal prostatic biopsy, directed via diffusion nuclear resonance, in patients with suspected prostate cancer and previous negative transrectal prostate biopsy. Urologia. 2021 Feb;88(1):69-76. doi: 10.1177/0391560320962888. Epub 2020 Oct 14. PMID: 33054607. |
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Martín-Serrano Á, Gonzalez-Morena JM, Barbero N, Ariza A, Sánchez Gómez FJ, Pérez-Inestrosa E, Pérez-Sala D, Torres MJ, Montañez MI. Biotin-Labelled Clavulanic Acid to Identify Proteins Target for Haptenation in Serum: Implications in Allergy Studies. Front Pharmacol. 2020 Nov 18;11:594755. doi: 10.3389/fphar.2020.594755. PMID: 33442385; PMCID: PMC7797785. |
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Pajares MA, Zimmerman T, Sánchez-Gómez FJ, Ariza A, Torres MJ, Blanca M, Cañada FJ, Montañez MI, Pérez-Sala D. Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency. Front Pharmacol. 2020 Mar 4;11:189. doi: 10.3389/fphar.2020.00189. PMID: 32210804; PMCID: PMC7065267. |
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García-Martín E, Sánchez-Gómez FJ, Amo G, García Menaya J, Cordobés C, Ayuso P, Plaza Serón MC, Blanca M, Campo P, Esguevillas G, Pajares MA, G Agúndez JA, Pérez-Sala D. Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels. Hum Mutat. 2018 Aug;39(8):1081-1091. doi: 10.1002/humu.23548. Epub 2018 May 25. PMID: 29726087. |
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Castellucci R, Linares Quevedo AI, Sánchez Gómez FJ, Díez Rodríguez J, Cogorno L, Cogollos Acuña I, Salmerón Béliz I, Muñoz Fernández de Legaría M, Martínez Piñeiro L. Prospective nonrandomized study of diagnostic accuracy comparing prostate cancer detection by transrectal ultrasound-guided biopsy to magnetic resonance imaging with subsequent MRI-guided biopsy in biopsy-naïve patients. Minerva Urol Nefrol. 2017 Dec;69(6):589-595. doi: 10.23736/S0393-2249.17.02845-4. PMID: 29094851. |
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Sánchez-Gómez FJ, González-Morena JM, Vida Y, Pérez-Inestrosa E, Blanca M, Torres MJ, Pérez-Sala D. Amoxicillin haptenates intracellular proteins that can be transported in exosomes to target cells. Allergy. 2017 Mar;72(3):385-396. doi: 10.1111/all.12958. Epub 2016 Jul 26. PMID: 27319758. |
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Sánchez-Gómez FJ, Díez-Dacal B, García-Martín E, Agúndez JA, Pajares MA, Pérez-Sala D. Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase. Front Pharmacol. 2016 Aug 4;7:237. doi: 10.3389/fphar.2016.00237. PMID: 27540362; PMCID: PMC4973429. |
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Gonzalez-Morena JM, Montanez MI, Aldini G, Sanchez-Gomez FJ, Perez-Sala D. Adduct Formation and Context Factors in Drug Hypersensitivity: Insight from Proteomic Studies. Curr Pharm Des. 2016;22(45):6748-6758. doi: 10.2174/1381612822666160927113748. PMID: 27779087. |
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Díez-Dacal B, Sánchez-Gómez FJ, Sánchez-Murcia PA, Milackova I, Zimmerman T, Ballekova J, García-Martín E, Agúndez JA, Gharbi S, Gago F, Stefek M, Pérez-Sala D. Molecular Interactions and Implications of Aldose Reductase Inhibition by PGA1 and Clinically Used Prostaglandins. Mol Pharmacol. 2016 Jan;89(1):42-52. doi: 10.1124/mol.115.100693. Epub 2015 Oct 20. PMID: 26487510. |
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Sanchis-Bonet A, Barrionuevo-González M, Bajo-Chueca A, Morales-Palacios N, Sanchez-Chapado M. Does [-2]Pro-Prostate Specific Antigen Meet the Criteria to Justify Its Inclusion in the Clinical Decision-Making Process?. Urol Int. 2018;100(2):146-154. doi: 10.1159/000481439. Epub 2018 Jan 18. PMID: 29346783. |
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Sanchís-Bonet A, Barrionuevo-González M, Bajo-Chueca AM, Pulido-Fonseca L, Ortega-Polledo LE, Tamayo-Ruiz JC, Sánchez-Chapado M. Validation of the prostate health index in a predictive model of prostate cancer. Actas Urol Esp (Engl Ed). 2018 Jan-Feb;42(1):25-32. English, Spanish. doi: 10.1016/j.acuro.2017.06.003. Epub 2017 Aug 12. PMID: 28811062. |
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Sanchis-Bonet A, Morales-Palacios N, Barrionuevo-Gonzalez M, Ortega-Polledo LE, Ortiz-Vico FJ, Sanchez-Chapado M. Does obesity modify prostate cancer detection in a European cohort?. Cent European J Urol. 2017;70(1):30-36. doi: 10.5173/ceju.2017.881. Epub 2017 Jan 3. PMID: 28461985; PMCID: PMC5407327. |
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Sanchís-Bonet A, Ortiz-Vico F, Morales-Palacios N, Sánchez-Chapado M. The association between metabolic syndrome and prostate cancer: Effect on its aggressiveness and progression. Actas Urol Esp. 2015 Apr;39(3):154-60. English, Spanish. doi: 10.1016/j.acuro.2014.09.009. Epub 2014 Nov 14. PMID: 25454266. |
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Cabrera Meirás F, Sanchís Bonet A, Blanco Carballo O, Martín Parada A, Duque Ruiz G, Leiva Galvis O. Absceso prostático por Staphilococo aureus y empiema subdural: presentación de un caso [Staphylococcus aureus prostatic abscess and subdural empyema: a case report]. Actas Urol Esp. 2007 May;31(5):548-52. Spanish. doi: 10.1016/s0210-4806(07)73680-x. PMID: 17711175. |
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Romero Otero J, Duarte Ojeda JM, Cruceyra Betriu G, Pérez-Martín ME, Sanchís Bonet A, Tejido Sánchez A, Leiva Galvis O. Adenocarcinoma vesical primario: nuestra experiencia [Primary adenocarcinoma of the urinary bladder: our experience]. Actas Urol Esp. 2005 Mar;29(3):257-60. Spanish. doi: 10.1016/s0210-4806(05)73236-8. PMID: 15945250. |
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Klett J, Gómez-Casero E, Méndez-Pertuz M, Urbano-Cuadrado M, Megias D, Blasco MA, Martínez S, Pastor J, Blanco-Aparicio C. Screening protocol for the identification of modulators by immunofluorescent cell-based assay. Chem Biol Drug Des. 2020 Jan;95(1):66-78. doi: 10.1111/cbdd.13616. Epub 2019 Sep 20. PMID: 31469231. |
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Morgado-Palacin L, Llanos S, Urbano-Cuadrado M, Blanco-Aparicio C, Megias D, Pastor J, Serrano M. Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway. Carcinogenesis. 2014 Dec;35(12):2822-30. doi: 10.1093/carcin/bgu220. Epub 2014 Oct 24. PMID: 25344835. |
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Aguado-Ullate S, Urbano-Cuadrado M, Villalba I, Pires E, García JI, Bo C, Carbó JJ. Predicting the enantioselectivity of the copper-catalysed cyclopropanation of alkenes by using quantitative quadrant-diagram representations of the catalysts. Chemistry. 2012 Oct 29;18(44):14026-36. doi: 10.1002/chem.201201135. Epub 2012 Sep 17. PMID: 22987760. |
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Rabal O, Urbano-Cuadrado M, Oyarzabal J. Computational medicinal chemistry in fragment-based drug discovery: what, how and when. Future Med Chem. 2011 Jan;3(1):95-134. doi: 10.4155/fmc.10.277. PMID: 21428828. |
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Urbano-Cuadrado M, Rabal O, Oyarzabal J. Centralizing discovery information: from logistics to knowledge at a public organization. Comb Chem High Throughput Screen. 2011 Jul;14(6):429-49. doi: 10.2174/138620711795767848. PMID: 21143181. |
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Oyarzabal J, Zarich N, Albarran MI, Palacios I, Urbano-Cuadrado M, Mateos G, Reymundo I, Rabal O, Salgado A, Corrionero A, Fominaya J, Pastor J, Bischoff JR. Discovery of mitogen-activated protein kinase-interacting kinase 1 inhibitors by a comprehensive fragment-oriented virtual screening approach. J Med Chem. 2010 Sep 23;53(18):6618-28. doi: 10.1021/jm1005513. PMID: 20722422. |
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Urbano-Cuadrado M, Carbó JJ, Maldonado AG, Bo C. New quantum mechanics-based three-dimensional molecular descriptors for use in QSSR approaches: application to asymmetric catalysis. J Chem Inf Model. 2007 Nov-Dec;47(6):2228-34. doi: 10.1021/ci700181v. Epub 2007 Oct 26. PMID: 17960899. |
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Ruiz IL, Urbano-Cuadrado M, Gómez-Nieto MA. Data fusion of similarity and dissimilarity measurements using Wiener-based indices for the prediction of the NPY Y5 receptor antagonist capacity of benzoxazinones. J Chem Inf Model. 2007 Nov-Dec;47(6):2235-41. doi: 10.1021/ci700180m. Epub 2007 Sep 29. PMID: 17902643. |
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Cuadrado MU, Ruiz IL, Gómez-Nieto MA. QSAR models based on isomorphic and nonisomorphic data fusion for predicting the blood brain barrier permeability. J Comput Chem. 2007 May;28(7):1252-60. doi: 10.1002/jcc.20671. PMID: 17299834. |
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Urbano Cuadrado M, Luque Ruiz I, Gómez-Nieto MA. Refinement and use of the approximate similarity in QSAR models for benzodiazepine receptor ligands. J Chem Inf Model. 2006 Sep-Oct;46(5):2022-9. doi: 10.1021/ci600216h. PMID: 16995733. |
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Villaescusa L, Zaragozá C, Zaragozá F, Tamargo J. Herbal medicines for the treatment of cardiovascular diseases: Benefits and risks - A narrative review. Int J Cardiol. 2023 Aug 15;385:44-52. doi: 10.1016/j.ijcard.2023.04.045. Epub 2023 Apr 26. PMID: 37116758. |
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Reventun P, Sánchez-Esteban S, Cook-Calvete A, Delgado-Marín M, Roza C, Jorquera-Ortega S, Hernandez I, Tesoro L, Botana L, Zamorano JL, Zaragoza C, Saura M. Endothelial ILK induces cardioprotection by preventing coronary microvascular dysfunction and endothelial-to-mesenchymal transition. Basic Res Cardiol. 2023 Jul 14;118(1):28. doi: 10.1007/s00395-023-00997-0. PMID: 37452166; PMCID: PMC10348984. |
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Paz-García M, Povo-Retana A, Jaén RI, Prieto P, Peraza DA, Zaragoza C, Hernandez-Jimenez M, Pineiro D, Regadera J, García-Bermejo ML, Rodríguez-Serrano EM, Sánchez-García S, Moro MA, Lizasoaín I, Delgado C, Valenzuela C, Boscá L. Beneficial effect of TLR4 blockade by a specific aptamer antagonist after acute myocardial infarction. Biomed Pharmacother. 2023 Feb;158:114214. doi: 10.1016/j.biopha.2023.114214. Epub 2023 Jan 4. PMID: 36916435. |
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Díaz Del Campo LS, García-Redondo AB, Rodríguez C, Zaragoza C, Duro-Sánchez S, Palmas F, de Benito-Bueno A, Socuéllamos PG, Peraza DA, Rodrigues-Díez R, Valenzuela C, Dalli J, Salaices M, Briones AM. Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension. Hypertension. 2023 Jan;80(1):84-96. doi: 10.1161/HYPERTENSIONAHA.122.19448. Epub 2022 Nov 7. PMID: 36337053. |
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Llauradó G, Vlacho B, Wargny M, Ruan Y, Franch-Nadal J, Domingo P, Gourdy P, Saulnier PJ, Hadjadj S, Wild SH, Rea R, Cariou B, Khunti K, Mauricio D; CORONADO, the ABCD COVID-19 diabetes national audit, HM Hospitales investigators and the Hospital del Mar - Hospital de la Santa Creu i Sant Pau Diabetes Research Group. The association between macrovascular complications and intensive care admission, invasive mechanical ventilation, and mortality in people with diabetes hospitalized for coronavirus disease-2019 (COVID-19). Cardiovasc Diabetol. 2022 Oct 19;21(1):216. doi: 10.1186/s12933-022-01657-8. PMID: 36261811; PMCID: PMC9580453. |
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Lacueva FJ, Escrig-Sos J, Marti-Obiol R, Zaragoza C, Mingol F, Oviedo M, Peris N, Civera J, Roig A; RECEG-CV group. Short-term postoperative outcomes of gastric adenocarcinoma patients treated with curative intent in low-volume centers. World J Surg Oncol. 2022 Oct 17;20(1):344. doi: 10.1186/s12957-022-02804-x. PMID: 36253780; PMCID: PMC9575241. |
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Saura M, Zamorano JL, Zaragoza C. Corrigendum: Preclinical models of congestive heart failure, advantages and limitations for application in clinical practice. Front Physiol. 2022 Oct 10;13:1045550. doi: 10.3389/fphys.2022.1045550. Erratum for: Front Physiol. 2022 Aug 04;13:850301. PMID: 36299254; PMCID: PMC9589883. |
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Tesoro L, Hernández I, Ramírez-Carracedo R, Díez-Mata J, Alcharani N, Jiménez-Guirado B, Ovejero-Paredes K, Filice M, Zamorano JL, Saura M, Zaragoza C, Botana L. NIL10: A New IL10-Receptor Binding Nanoparticle That Induces Cardiac Protection in Mice and Pigs Subjected to Acute Myocardial Infarction through STAT3/NF-κB Activation. Pharmaceutics. 2022 Sep 26;14(10):2044. doi: 10.3390/pharmaceutics14102044. PMID: 36297479; PMCID: PMC9608724. |
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Sánchez-Esteban S, Castro-Pinto M, Cook-Calvete A, Reventún P, Delgado-Marín M, Benito-Manzanaro L, Hernandez I, López-Menendez J, Zamorano JL, Zaragoza C, Saura M. Integrin-Linked Kinase Expression in Human Valve Endothelial Cells Plays a Protective Role in Calcific Aortic Valve Disease. Antioxidants (Basel). 2022 Aug 31;11(9):1736. doi: 10.3390/antiox11091736. PMID: 36139812; PMCID: PMC9495882. |
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Saura M, Zamorano JL, Zaragoza C. Preclinical models of congestive heart failure, advantages, and limitations for application in clinical practice. Front Physiol. 2022 Aug 4;13:850301. doi: 10.3389/fphys.2022.850301. Erratum in: Front Physiol. 2022 Oct 10;13:1045550. PMID: 35991184; PMCID: PMC9386157. |
